Results 161 to 170 of about 3,834,350 (184)

Thermodynamics and Molecule Landscape of Protein Corona

Nano Letters
The protein corona redefines interfacial identity and dictates subsequent biological responses of nanoparticles. Nevertheless, the thermodynamic principles governing its formation and spatiotemporal evolution at the single-particle level remain poorly resolved.
Ruoyu Hu, Xinyu Gong, Yanan Liu, Lei Xu, Zixiao Wang, Hui Wang   +5 more
openaire   +2 more sources

Understanding the Elusive Protein Corona of Thermoresponsive Nanogels

Nanomedicine, 2018
We analyzed the protein corona of thermoresponsive, poly(N-isopropylacrylamide)- or poly(N-isopropylmethacrylamide)-based nanogels.Traces of protein corona detected after incubation in human serum were characterized by proteomics and dynamic light scattering in undiluted serum.Apolipoprotein B-100 and albumin were the main components of the protein ...
Miceli, E., Kuropka, B., Rosenauer, C., Blanco, E., Theune, L., Kar, M., Weise, C., Morsbach, S., Freund, C., Calderon, M.   +9 more
openaire   +3 more sources

Disease specific protein corona

SPIE Proceedings, 2015
It is now well accepted that upon their entrance into the biological environments, the surface of nanomaterials would be covered by various biomacromolecules ( e.g., proteins and lipids). The absorption of these biomolecules, so called ‘protein corona’, onto the surface of (nano)biomaterials confers them a new ‘biological identity’.
M. Rahman, M. Mahmoudi
openaire   +1 more source

Studying the Protein Corona on Nanoparticles by FCS

2013
Engineered nanoparticles (NPs) have found widespread application in technology and medicine. Whenever they come in contact with a living organism, interactions take place between the surfaces of the NPs and biomatter, in particular proteins, which are currently not well understood. We have introduced fluorescence correlation spectroscopy (FCS) and dual-
Nienhaus, G. U., Maffre, P., Nienhaus, K.   +2 more
openaire   +3 more sources

Protein Corona: Applications and Challenges

2013
The protein corona introduces new unexpected applications and shortcomings for the nanoparticles. For instance, it is now well recognized that the protein coating reduces the targeting capability of surface-engineered nanoparticles by screening the active sites of the targeting ligands.
Masoud Rahman, Sophie Laurent, Nancy Tawil, L’Hocine Yahia, Morteza Mahmoudi   +4 more
openaire   +1 more source

Nanoparticle-Protein Interaction: The Significance and Role of Protein Corona

2018
The physico-chemical properties of nanoparticles, as characterized under idealized laboratory conditions, have been suggested to differ significantly when studied under complex physiological environments. A major reason for this variation has been the adsorption of biomolecules (mainly proteins) on the nanoparticle surface, constituting the so-called ...
Saad Mohammad, Ahsan, Chintalagiri Mohan, Rao, Md Faiz, Ahmad   +2 more
openaire   +2 more sources

The Protein Corona From Nanomedicine to Environmental Science

Nature Reviews Materials, 2023
Roxana Coreas, Morteza Mahmoudi, Anna Moore   +2 more
exaly  

Protein Corona: Friend or Foe? Co-Opting Serum Proteins for Nanoparticle Delivery

Advanced Drug Delivery Reviews, 2023
Yoon Yeo, Yongzhe Li, Yanying He
exaly  

Composition of Intracellular Protein Corona Around Nanoparticles During Internalization

ACS Nano, 2021
Beibei Chen, Man He, Bin Hu
exaly  

An Analysis of the Binding Function and Structural Organization of the Protein Corona

Journal of the American Chemical Society, 2020
Warren Chan, Jamie L Y Wu, Yuwei Zhang
exaly