Results 141 to 150 of about 3,834,350 (184)

A Protein Corona-Based Diagnostic Tool for Eroded Atherosclerotic Plaques. [PDF]

Small
Tobar Leitão SA, Sausen G, Liu Y, Yu Y, Greco A, Molinaro R, Farokhzad OC, Corbo C, Libby P.   +8 more
europepmc   +1 more source

Mechanistic Insights into Protein Corona Formation: The Surface Charge of Mesoporous Silica Nanoparticles Determines the Orientation and the Conformation of Adsorbed BSA Protein. [PDF]

Langmuir
Ballicu A, Meloni GM, Farci M, Tocco D, Piludu M, Parsons DF, Carucci C, Jachimska B, Salis A.   +8 more
europepmc   +1 more source

Multiplexed Nanoparticle Protein Corona Enables Accurate and Precise Deep Plasma Proteomics. [PDF]

J Proteome Res
Huang T, Wang J, Stukalov A, Kreimer S, Zhao X, Cantrell LS, Zhou X, Brewer A, Ho G, Murolo F, Quach K, Figa M, Just S, Castro G, Elgierari E, Benz RW, Motamedchaboki K, Batzoglou S, Farokhzad OC, Van Eyk JE, Siddiqui A.   +20 more
europepmc   +1 more source

An Overview of Nanoparticle Protein Corona Literature

Small, 2023
Abstract The protein corona forms spontaneously on nanoparticle surfaces when nanomaterials are introduced into any biological system/fluid. Reliable characterization of the protein corona is, therefore, a vital step in the development of safe and efficient diagnostic and therapeutic nanomedicine products.
Morteza Mahmoudi, Markita P. Landry
exaly   +4 more sources

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Spotlight on the Protein Corona of Liposomes

Acta Biomaterialia, 2021
Although an established drug delivery platform, liposomes have not fulfilled their true potential. In the body, interactions of liposomes are mediated by the layer of plasma proteins adsorbed on the surface, the protein corona. The review aims to collect the data of the last decade on liposome protein corona, tracing the path from interactions of ...
Natalia R. Onishchenko, Daria S. Tretiakova, Elena L. Vodovozova   +2 more
openaire   +2 more sources

Hard and Soft Protein Corona of Nanomaterials: Analysis and Relevance [PDF]

Nanomaterials, 2021
Upon contact with a biological milieu, nanomaterials tend to interact with biomolecules present in the media, especially proteins, leading to the formation of the so-called “protein corona”. As a result of these nanomaterial–protein interactions, the bio-
María Vallet Regí, Rafaela Garcia-Alvarez   +1 more
exaly   +2 more sources

Chemical and Biophysical Signatures of the Protein Corona in Nanomedicine

Journal of the American Chemical Society, 2022
An inconvenient hurdle in the practice of nanomedicine is the protein corona, a spontaneous collection of biomolecular species by nanoparticles in living systems. The protein corona is dynamic in composition and may entail improved water suspendability and compromised delivery and targeting to the nanoparticles.
Feng Ding, Rong Cai, Nikolaos Andrikopoulos   +2 more
exaly   +5 more sources

Time Evolution of the Nanoparticle Protein Corona

ACS Nano, 2010
In this work, we explore the formation of the protein corona after exposure of metallic Au nanoparticles (NPs), with sizes ranging from 4 to 40 nm, to cell culture media containing 10% of fetal bovine serum. Under in vitro cell culture conditions, zeta potential measurements, UV-vis spectroscopy, dynamic light scattering and transmission electron ...
Gertie J Oostingh, Victor Puntes, Eudald Casals   +2 more
exaly   +3 more sources

Interplay between nanomedicine and protein corona

Journal of Materials Chemistry B, 2021
Protein corona (PC) severely affects the in vivo performance of nanomedicines. Regulation of interplay between nanomedicines and PC may provide a new avenue for precise medication.
Min Yang, Ercan Wu, Wenjing Tang, Jun Qian, Changyou Zhan   +4 more
openaire   +2 more sources