Results 241 to 250 of about 178,624 (341)

Insights into outer membrane protein crystallization

, 2008
Simon Newstead, Jeanette R. Hobbs, Davina Jordan, Elisabeth P. Carpenter, So Iwata   +4 more
openalex   +2 more sources

GSH as an A‐A Type Allosteric Activator of PKM2: Modulating Cancer Cell Homeostasis and Ferroptosis Susceptibility

Advanced Science, EarlyView.
Glutathione (GSH) defines oxidative balance, but can it directly tune central metabolism? The research reveals that GSH binds and potently activates pyruvate kniase M2 (PKM2), rewiring glycolysis and dictating ferroptosis sensitivity. Combining GSH depletion with PKM2 activation triggers mitochondrial damage and lipid peroxidation, profoundly ...
Tsan‐Jan Chen, Chi‐Jen Lo, Meng‐Jen Wu, Wei Yang Sit, Hsin‐Yu Hsu, Yi‐Cheng Huang, Chien‐Hung Lu, Yu‐Lun Chen, Wei‐Kai Fang, Shan‐Min Yang, Pei‐Lien Chen, Tokuko Haraguchi, Yasushi Hiraoka, Chun‐Yu Lin, Mei‐Ling Cheng, Muh‐Hwa Yang, Hsing‐Jien Kung, Wen‐Ching Wang   +17 more
wiley   +1 more source

Spectroscopic insights into multi-phase protein crystallization in complex lysate using Raman spectroscopy and a particle-free bypass. [PDF]

Front Bioeng Biotechnol
Wegner CH, Eming SM, Walla B, Bischoff D, Weuster-Botz D, Hubbuch J.   +5 more
europepmc   +1 more source

All Nanozyme‐Based Cascade Reactions for Biomedical Applications: from Self‐Cascading Nanozyme to Immobilized Cascade Nanozyme

Advanced Science, EarlyView.
This review introduces the development and classification of all‐nanozyme cascade reaction systems, highlighting mechanistic insights and research methods for understanding catalytic features and design principles. It provides detailed classifications, surveys recent applications in biosensing and therapy, and discusses the challenges that all‐nanozyme
Caixia Zhu, Congcong Jiang, Hian Kee Lee, Yuanjian Zhang, Sheng Tang   +4 more
wiley   +1 more source

TMCrys: predict propensity of success for transmembrane protein crystallization. [PDF]

Bioinformatics, 2018
Varga JK, Tusnády GE.
europepmc   +1 more source

Protein crystallization in microgravity.

, 1997
Shigeo Aibara, Katsumi Shibata, Yuhei Morita   +2 more
openalex   +2 more sources

Traceless Regulation of Genetic Circuitry

Advanced Science, EarlyView.
Energy‐based, as opposed to molecular, control offers unprecedented improvements in key circuit parameters. This review summarizes the fundamentals of such traceless switches, categorizes them by trigger modalities, and compares and contrasts distinct advantages as well as shortcomings of each kind.
Gokberk Unal, Martin Fussenegger
wiley   +1 more source

Critical evaluation of bioinformatics tools for the prediction of protein crystallization propensity. [PDF]

Brief Bioinform, 2018
Wang H, Feng L, Webb GI, Kurgan L, Song J, Lin D.   +5 more
europepmc   +1 more source

Recent Progress in Mechanoluminescence for Multi‐Dimensional Stress Monitoring

Advanced Science, EarlyView.
Multi‐dimensional stress visualization technology (0D point detection, 1D linear distribution, 2D planar imaging, 3D volume reconstruction) has become a focus of attention in the field of stress sensing. The transition from “points” to “multi‐dimensional spatial fields” facilitates real‐time, in situ, and high‐resolution visualization of stress ...
Xiuxia Yang, Ting Wang, Lei Zhao, Xuhui Xu   +3 more
wiley   +1 more source

X-ray transparent microfluidic platforms for membrane protein crystallization with microseeds. [PDF]

Lab Chip, 2018
Schieferstein JM, Pawate AS, Varel MJ, Guha S, Astrauskaite I, Gennis RB, Kenis PJA.   +6 more
europepmc   +1 more source