Results 301 to 310 of about 178,624 (341)

An Airlift Crystallizer for Protein Crystallization

Industrial & Engineering Chemistry Research, 2019
Crystallization is an attractive separation and purification technique for proteins. However, protein crystallization often suffers from long batch times due to slow crystallization kinetics. Furthermore, brittle protein crystals may be subject to attrition in conventional crystallizers. An airlift crystallizer is fabricated using three-dimensional (3D)
Kiran Mathew Thomas, Richard Lakerveld
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Making protein crystals fly

Nature Methods, 2014
A new device for injecting membrane-protein microcrystals into the path of an X-ray free-electron laser beam improves the efficiency of serial femtosecond crystallography.
openaire   +2 more sources

Protein–protein interaction at crystal contacts

Proteins: Structure, Function, and Bioinformatics, 1995
AbstractPacking contacts are crystal artifacts, yet they make use of the same forces that govern specific recognition in protein‐protein complexes and oligomeric proteins. They provide examples of a nonspecific protein‐protein interaction which can be compared to biologically relevant ones.
J, Janin, F, Rodier
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Protein Single Crystal Diffraction

1988
37 5 Exploitation of the High Intensity and Superior Collimation of SR (with case Studies) . . . . . . . . . . . . . . . . . . . . . . . . . . 39 5.1 General . . . . . . . . . . . . . . . . . . . . . . . . . . . . 39 5.2 Reduct ion o f Radia t ion Damage . . . . . . . . . . . . . . . . . . 40 5.3 Large Uni t Cells . . . . . . . . . . . . . . . . . . . .
Ian D. Glover, John R. Helliwell, Miroslav Z. Papiz   +2 more
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Crystallization of Nitrogenase Proteins

2018
Nitrogenase is the only known enzymatic system capable of reducing atmospheric dinitrogen to ammonia. This unique reaction requires tightly choreographed interactions between the nitrogenase component proteins, the molybdenum-iron (MoFe)- and iron (Fe)-proteins, as well as regulation of electron transfer between multiple metal centers that are only ...
Wenke, Belinda B., Arias, Renee J., Spatzal, Thomas   +2 more
openaire   +3 more sources

Crystallization of membrane proteins

Trends in Biochemical Sciences, 1983
Abstract After a long period of fruitless attempts, three-dimensional crystal of membrane proteins are now available. The best of the crystals are suited for high-resolution structure determination by X-ray crystallography. The use of small detergents and small amphiphilic molecules during crystallization proved to be of great value.
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Protein crystallization

Photosynthesis Research, 2009
Mei, Li, Wen-rui, Chang
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High-throughput protein crystallization

Current Opinion in Structural Biology, 2000
The combinatorial chemistry industry has made major advances in the handling and mixing of small volumes, and in the development of robust liquid-handling systems. In addition, developments have been made in the area of material handling for the high-throughput drug screening and combinatorial chemistry fields.
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High-Throughput Protein Crystallization

2009
Structural genomics projects have led to great progress in the field of structural biology. Considerable advances have been made in the automation of all stages of the pipeline from clone to structure. This chapter focuses on crystallization that is one of the major bottlenecks in this pipeline.
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Nucleation of protein crystals

Journal of Structural Biology, 2003
This paper introduces nucleation theory applied to crystallizing protein solutions. It is shown that the classical approach explains the available nucleation data under most conditions used for growing protein crystals for structural studies and for industrial crystallization.
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