Results 181 to 190 of about 103,093 (251)

Metal‐Directed Self‐Assembly in a Beta‐Sheet Miniprotein Scaffold

open access: yesEuropean Journal of Inorganic Chemistry, Volume 29, Issue 7, 2 March 2026.
A rationally engineered miniprotein, V14C, which is based on the beta β‐sheet Foldon domain, self‐assembles via a metal‐binding site to form well‐defined oligomers in the presence of Zn2+, Hg2+, and Cd2+. This modular design expands the toolbox for creating custom metalloproteins, enabling studies of metal–protein interactions for biochemical functions
Chandan Muni Reddy   +3 more
wiley   +1 more source

Optimizing Crystal Size of Photosystem II by Macroseeding: Toward Neutron Protein Crystallography. [PDF]

open access: yesCryst Growth Des, 2018
Hussein R   +9 more
europepmc   +1 more source

Homologous expression and purification of human HAX‐1 for structural studies

open access: yesFEBS Open Bio, Volume 16, Issue 3, Page 450-460, March 2026.
This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley   +1 more source

Protein Crystallography in Vaccine Research and Development. [PDF]

open access: yesInt J Mol Sci, 2015
Malito E, Carfi A, Bottomley MJ.
europepmc   +1 more source

Cinnamic‐Hydroxamic‐Acid Derivatives Exhibit Antibiotic, Anti‐Biofilm, and Supercoiling Relaxation Properties by Targeting Bacterial Nucleoid‐Associated Protein HU

open access: yesAdvanced Science, Volume 13, Issue 13, 3 March 2026.
Cinnamic‐hydroxamic‐acid derivatives (CHADs) are identified as novel inhibitors of the bacterial nucleoid‐associated protein HU, exhibiting potent antibacterial, anti‐biofilm (both inhibition and eradication), and DNA relaxation (anti‐supercoiling) activities. Moreover, CHADs demonstrate strong synergistic effects with multiple antibiotics.
Huan Chen   +22 more
wiley   +1 more source

Surface‐Enhanced Raman Spectroscopy for Acrylamide Detection Using Gold Nanoparticles on Titanium Oxide Nanowires: A Green Analytical Method

open access: yesAnalysis &Sensing, Volume 6, Issue 2, March 2026.
Acrylamide is found in many common foods and presents toxicity concerns. Its current detection methods are time consuming, costly, and environmentally unsustainable. This study presents an acrylamide detection methodology based on surface enhanced Raman spectroscopy (SERS) using gold nanoparticles on titanium oxide nanowires, with focus on reducing ...
Maria Tarapoulouzi   +5 more
wiley   +1 more source

Probing Attractive OH−π Interactions and Repulsive n−π Interactions in a Phenol Molecular Balance

open access: yesChemistry – An Asian Journal, Volume 21, Issue 5, 13 March 2026.
This work introduces a 2,6‐diarylphenol molecular balance that enables direct comparison of competing intramolecular attractive OH–π interactions and repulsive O–π interactions. Through combined experimental and computational studies, we show that the phenolic OH group selectively interacts with electron‐rich aromatic rings by avoiding repulsive O–π ...
Jie Jian   +5 more
wiley   +1 more source

Light‐Based Molecular Tools to Precisely Monitor and Operate β‐Adrenoceptors

open access: yesMedicinal Research Reviews, Volume 46, Issue 2, Page 445-474, March 2026.
ABSTRACT β‐Adrenoceptors are important G protein–coupled receptors involved in cardiovascular, metabolic, and neurological regulation. To study their function with high precision, light‐based molecular tools have been developed offering precise spatiotemporal control.
Ignazzitto Maria Tindara   +3 more
wiley   +1 more source

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