Results 61 to 70 of about 103,093 (251)

Structural snapshot of a bacterial phytochrome in its functional intermediate state

Nature Communications, 2018
Phytochromes are photoreceptors that are present in plants, bacteria and fungi. Here the authors present crystal structures of the phytochrome Agp2 from Agrobacterium fabrum in the parent Pfr state as well as a functional Meta-F intermediate and discuss ...
Andrea Schmidt, Luisa Sauthof, Michal Szczepek, Maria Fernandez Lopez, Francisco Velazquez Escobar, Bilal M. Qureshi, Norbert Michael, David Buhrke, Tammo Stevens, Dennis Kwiatkowski, David von Stetten, Maria Andrea Mroginski, Norbert Krauß, Tilman Lamparter, Peter Hildebrandt, Patrick Scheerer   +15 more
doaj   +1 more source

Arginine Methylation Antagonizes TEAD3‐Mediated Repression to Promote Osteogenic Differentiation by Disrupting RUNX2‐Sequestrating Condensates

Advanced Science, EarlyView.
In the unmethylated state, TEAD forms stable, repressive condensates that sequester the osteogenic master regulator RUNX2. Arginine methylation of TEAD at R55 acts as a molecular brake, dissolving these condensates to release RUNX2 and activate the osteogenic program.
Lei Cao, Ruohui Han, Hui Xiong, Qian Li, Shaofei Tao, Xudong Wu, Dayong Liu   +6 more
wiley   +1 more source

New Trends in Protein Crystallization and Protein Crystallography

Crystals, 2020
Biological crystals and their properties have recently unveiled the complex mechanisms where life is supported [...]
Abel Moreno
doaj   +1 more source

opXRD: Open Experimental Powder X‐Ray Diffraction Database

Advanced Intelligent Discovery, EarlyView.
We introduce the Open Experimental Powder X‐ray Diffraction Database, the largest openly accessible collection of experimental powder diffractograms, comprising over 92,000 patterns collected across diverse material classes and experimental setups. Our ongoing effort aims to guide machine learning research toward fully automated analysis of pXRD data ...
Daniel Hollarek, Henrik Schopmans, Jona Östreicher, Jonas Teufel, Bin Cao, Adie Alwen, Simon Schweidler, Mriganka Singh, Tim Kodalle, Hanlin Hu, Gregoire Heymans, Maged Abdelsamie, Arthur Hardiagon, Alexander Wieczorek, Siarhei Zhuk, Ruth Schwaiger, Sebastian Siol, François‐Xavier Coudert, Moritz Wolf, Carolin M. Sutter‐Fella, Ben Breitung, Andrea M. Hodge, Tong‐yi Zhang, Pascal Friederich   +23 more
wiley   +1 more source

(Poly)Borylated Species as Modern Reactive Groups toward Unusual Synthetic Applications

Angewandte Chemie, EarlyView.
In this review, we spotlight recent breakthroughs in α‐polyboron‐substituted carbon‐centered intermediates (carbanion, carbocation, radical, and carbene) and polyborylated alkenes. By bridging fundamental reactivity with the application potential of these extraordinary species, we hope this review will serve as a roadmap for harnessing these unique ...
Nadim Eghbarieh, Nicole Hanania, Pinaki Nad, Tipu Alam, Tamir Kish, Ahmad Masarwa   +5 more
wiley   +2 more sources

Reimagining o‐Carborane‐Based Fluorophores: Charge‐Transfer from Boron Substituents Triggers Aggregation‐ and Crystallization‐Induced Emission

Angewandte Chemie, EarlyView.
This work reports, for the first time, aggregation‐ or crystallization‐induced emission in boron‐substituted carboranes, which was driven by photoinduced charge‐transfer from fluorophore attached via boron vertices. The emission properties can be tuned by varying the substituents, expanding design strategies for luminescent materials.
Balázs Szathmári, Yanhong Gao, Dániel Buzsáki, Dániel Zámbó, Tamás Holczbauer, Antal Udvardy, Pál Szabó, Júlia Kertész, Dóra Hessz, Zsolt Kelemen   +9 more
wiley   +2 more sources

Avoidable errors in deposited macromolecular structures: an impediment to efficient data mining

IUCrJ, 2014
Whereas the vast majority of the more than 85 000 crystal structures of macromolecules currently deposited in the Protein Data Bank are of high quality, some suffer from a variety of imperfections.
Zbigniew Dauter, Alexander Wlodawer, Wladek Minor, Mariusz Jaskolski, Bernhard Rupp   +4 more
doaj   +1 more source

The crystal structure of Acinetobacter baumannii bacterioferritin reveals a heteropolymer of bacterioferritin and ferritin subunits

Scientific Reports
Iron storage proteins, e.g., vertebrate ferritin, and the ferritin-like bacterioferritin (Bfr) and bacterial ferritin (Ftn), are spherical, hollow proteins that catalyze the oxidation of Fe2+ at binuclear iron ferroxidase centers (FOC) and store the Fe3+
Huili Yao, Suliat Alli, Lijun Liu, Anabel Soldano, Anne Cooper, Leo Fontenot, Dristen Verdin, Kevin P. Battaile, Scott Lovell, Mario Rivera   +9 more
doaj   +1 more source

STARS: Spread the beauty of DNA Crystallography [PDF]

Structural Dynamics
Very few freshmen at Georgia Tech have heard about DNA or Protein crystallography, not to mention its importance in structural advancement of protein functions, or let alone its beauty in nature.
Chenyi Andrew, Susanna Huang
doaj   +1 more source

Unusual traits shape the architecture of the Ig ancestor molecule

Communications Biology
Understanding the ancestral Ig domain’s molecular structure and tracing the evolution of Ig-like proteins are fundamental components missing from our comprehension of their evolutionary trajectory and function.
Alejandro Urdiciain, Thomas Madej, Jiyao Wang, James Song, Elena Erausquin, Philippe Youkharibache, Jacinto López-Sagaseta   +6 more
doaj   +1 more source