Results 41 to 50 of about 103,740 (157)

Structural snapshot of a bacterial phytochrome in its functional intermediate state

Nature Communications, 2018
Phytochromes are photoreceptors that are present in plants, bacteria and fungi. Here the authors present crystal structures of the phytochrome Agp2 from Agrobacterium fabrum in the parent Pfr state as well as a functional Meta-F intermediate and discuss ...
Andrea Schmidt, Luisa Sauthof, Michal Szczepek, Maria Fernandez Lopez, Francisco Velazquez Escobar, Bilal M. Qureshi, Norbert Michael, David Buhrke, Tammo Stevens, Dennis Kwiatkowski, David von Stetten, Maria Andrea Mroginski, Norbert Krauß, Tilman Lamparter, Peter Hildebrandt, Patrick Scheerer   +15 more
doaj   +1 more source

New Trends in Protein Crystallization and Protein Crystallography

Crystals, 2020
Biological crystals and their properties have recently unveiled the complex mechanisms where life is supported [...]
Abel Moreno
doaj   +1 more source

Avoidable errors in deposited macromolecular structures: an impediment to efficient data mining

IUCrJ, 2014
Whereas the vast majority of the more than 85 000 crystal structures of macromolecules currently deposited in the Protein Data Bank are of high quality, some suffer from a variety of imperfections.
Zbigniew Dauter, Alexander Wlodawer, Wladek Minor, Mariusz Jaskolski, Bernhard Rupp   +4 more
doaj   +1 more source

STARS: Spread the beauty of DNA Crystallography [PDF]

Structural Dynamics
Very few freshmen at Georgia Tech have heard about DNA or Protein crystallography, not to mention its importance in structural advancement of protein functions, or let alone its beauty in nature.
Chenyi Andrew, Susanna Huang
doaj   +1 more source

Protein X-ray Crystallography and Drug Discovery

Molecules, 2020
With the advent of structural biology in the drug discovery process, medicinal chemists gained the opportunity to use detailed structural information in order to progress screening hits into leads or drug candidates.
Laurent Maveyraud, Lionel Mourey
doaj   +1 more source

The crystal structure of Acinetobacter baumannii bacterioferritin reveals a heteropolymer of bacterioferritin and ferritin subunits

Scientific Reports
Iron storage proteins, e.g., vertebrate ferritin, and the ferritin-like bacterioferritin (Bfr) and bacterial ferritin (Ftn), are spherical, hollow proteins that catalyze the oxidation of Fe2+ at binuclear iron ferroxidase centers (FOC) and store the Fe3+
Huili Yao, Suliat Alli, Lijun Liu, Anabel Soldano, Anne Cooper, Leo Fontenot, Dristen Verdin, Kevin P. Battaile, Scott Lovell, Mario Rivera   +9 more
doaj   +1 more source

Unusual traits shape the architecture of the Ig ancestor molecule

Communications Biology
Understanding the ancestral Ig domain’s molecular structure and tracing the evolution of Ig-like proteins are fundamental components missing from our comprehension of their evolutionary trajectory and function.
Alejandro Urdiciain, Thomas Madej, Jiyao Wang, James Song, Elena Erausquin, Philippe Youkharibache, Jacinto López-Sagaseta   +6 more
doaj   +1 more source

Biocrystallography in Switzerland: Achievements and Future Perspectives

CHIMIA, 2014
The first protein crystallography group in Switzerland was installed at the Biozentrum of the University of Basel approximately 40 years ago.
Markus G. Grütter
doaj   +1 more source

A multi-reservoir extruder for time-resolved serial protein crystallography and compound screening at X-ray free-electron lasers. [PDF]

Nat Commun, 2023
Wranik M, Kepa MW, Beale EV, James D, Bertrand Q, Weinert T, Furrer A, Glover H, Gashi D, Carrillo M, Kondo Y, Stipp RT, Khusainov G, Nass K, Ozerov D, Cirelli C, Johnson PJM, Dworkowski F, Beale JH, Stubbs S, Zamofing T, Schneider M, Krauskopf K, Gao L, Thorn-Seshold O, Bostedt C, Bacellar C, Steinmetz MO, Milne C, Standfuss J.   +29 more
europepmc   +2 more sources

Pseudomonas aeruginosa gene PA4880 encodes a Dps-like protein with a Dps fold, bacterioferritin-type ferroxidase centers, and endonuclease activity

Frontiers in Molecular Biosciences
We report the biochemical, structural, and functional characterization of the protein coded by gene PA4880 in the P. aeruginosa PAO1 genome. The PA4880 gene had been annotated as coding a probable bacterioferritin.
Nimesha Rajapaksha, Huili Yao, Aisha Cook, Steve Seibold, Lijun Liu, Kevin P. Battaile, Leo Fontenot, Fabrizio Donnarumma, Scott Lovell, Mario Rivera   +9 more
doaj   +1 more source