Results 61 to 70 of about 103,740 (157)

Exploring serial crystallography for drug discovery

IUCrJ
Structure-based drug design is highly dependent on the availability of structures of the protein of interest in complex with lead compounds. Ideally, this information can be used to guide the chemical optimization of a compound into a pharmaceutical drug
A. Dunge, C. Phan, O. Uwangue, M. Bjelcic, J. Gunnarsson, G. Wehlander, H. Käck, G. Brändén   +7 more
doaj   +1 more source

Roles of inter- and intramolecular tryptophan interactions in membrane-active proteins revealed by racemic protein crystallography. [PDF]

Commun Chem, 2023
Lander AJ, Mercado LD, Li X, Taily IM, Findlay BL, Jin Y, Luk LYP.   +6 more
europepmc   +1 more source

Remote laboratory training for high school students: grocery store based hands-on project in protein crystallography. [PDF]

J Appl Crystallogr, 2023
Fox AL, Teteris AR, Mathews II.
europepmc   +1 more source

Understanding Cysteine Chemistry Using Conventional and Serial X-Ray Protein Crystallography. [PDF]

Crystals (Basel), 2022
Smith N, Wilson MA.
europepmc   +1 more source

Implementation of wedged-serial protein crystallography at PROXIMA-1. [PDF]

J Synchrotron Radiat, 2022
Chaussavoine I, Isabet T, Lener R, Montaville P, Vasireddi R, Chavas LMG.   +5 more
europepmc   +1 more source

Development of selective ssDNA micro-probe for PD1 detection as a novel strategy for cancer imaging

Scientific Reports
Programmed death receptor 1, PD1, modulates the function of immune cells by providing inhibitory signals and constitutes the marker of immune exhaustion. Monitoring the level of PD1 promises a useful diagnostic approach in autoimmune diseases and cancer.
Stanisław Malicki, Anna Czarna, Edyta Żyła, Barbara Pucelik, Wojciech Gałan, Barbara Chruścicka, Marta Kamińska, Alicja Sochaj-Gregorczyk, Katarzyna Magiera-Mularz, Jun Wang, Marek Winiarski, Małgorzata Benedyk-Machaczka, Joanna Kozieł, Grzegorz Dubin, Piotr Mydel   +14 more
doaj   +1 more source

Acoustic levitation and rotation of thin films and their application for room temperature protein crystallography. [PDF]

Sci Rep, 2022
Kepa MW, Tomizaki T, Sato Y, Ozerov D, Sekiguchi H, Yasuda N, Aoyama K, Skopintsev P, Standfuss J, Cheng R, Hennig M, Tsujino S.   +11 more
europepmc   +1 more source

Protein crystallography [PDF]

Acta Crystallographica Section A Foundations of Crystallography, 1996
openaire   +1 more source

Publisher Correction: Acoustic levitation and rotation of thin films and their application for room temperature protein crystallography. [PDF]

Sci Rep, 2022
Kepa MW, Tomizaki T, Sato Y, Ozerov D, Sekiguchi H, Yasuda N, Aoyama K, Skopintsev P, Standfuss J, Cheng R, Hennig M, Tsujino S.   +11 more
europepmc   +1 more source

Simulating diffraction photographs based on molecular dynamics trajectories of a protein crystal: a new option to examine structure-solving strategies in protein crystallography. [PDF]

IUCrJ, 2023
Liu N, Mikhailovskii O, Skrynnikov NR, Xue Y.   +3 more
europepmc   +1 more source