Results 21 to 30 of about 4,121,048 (281)

Protein crystallography beamline BL2S1 at the Aichi synchrotron. [PDF]

J Synchrotron Radiat, 2017
Watanabe N, Nagae T, Yamada Y, Tomita A, Matsugaki N, Tabuchi M.   +5 more
europepmc   +2 more sources

Radiation damage to nucleoprotein complexes in macromolecular crystallography [PDF]

, 2015
Significant progress has been made in macromolecular crystallography over recent years in both the understanding and mitigation of X-ray induced radiation damage when collecting diffraction data from crystalline proteins.
Ravelli, Raimond B. G., Mcgeehan, John E., Bury, Charles, Kneale, Geoff, Garman, Elspeth F., Ginn, Helen Mary, Carmichael, Ian, I. Carmichael (2645569), G. Kneale (20134014), C. Bury (20132679), R. B. G. Ravelli (20134011), H. M. Ginn (20134008), J. E. McGeehan (20132787), E. F. Garman (20115030)   +13 more
core   +1 more source

Crystal Structure of Ribosome-Inactivating Protein Ricin A Chain in Complex with the C-Terminal Peptide of the Ribosomal Stalk Protein P2

Toxins, 2016
Ricin is a type 2 ribosome-inactivating protein (RIP), containing a catalytic A chain and a lectin-like B chain. It inhibits protein synthesis by depurinating the N-glycosidic bond at α-sarcin/ricin loop (SRL) of the 28S rRNA, which thereby prevents the ...
Wei-Wei Shi, Yun-Sang Tang, See-Yuen Sze, Zhen-Ning Zhu, Kam-Bo Wong, Pang-Chui Shaw   +5 more
doaj   +1 more source

An extended motif in the SARS-CoV-2 spike modulates binding and release of host coatomer in retrograde trafficking

Communications Biology, 2022
The cytosolic tail of β-coronavirus spike proteins contains dibasic motifs that must be able to bind to the host’s coatomer protein-I (COPI) for trafficking and be released for viral assembly in the ER-Golgi intermediate compartment.
Debajit Dey, Suruchi Singh, Saif Khan, Matthew Martin, Nicholas J. Schnicker, Lokesh Gakhar, Brian G. Pierce, S. Saif Hasan   +7 more
doaj   +1 more source

Structural and mutagenic analysis of the RM controller protein C.Esp1396I [PDF]

, 2014
Bacterial restriction-modification (RM) systems are comprised of two complementary enzymatic activities that prevent the establishment of foreign DNA in a bacterial cell: DNA methylation and DNA restriction.
Martin, Richard N. A., Kneale, Geoff, John E McGeehan, Geoff Kneale, Geoff Kneale (22086), Mcgeehan, John, Richard N A Martin, Richard N. A. Martin (571238), John E. McGeehan (431702), McGeehan John E., Martin Richard N. A., Kneale Geoff   +11 more
core   +2 more sources

Structures and Ribosomal Interaction of Ribosome-Inactivating Proteins

Molecules, 2016
Ribosome-inactivating proteins (RIPs) including ricin, Shiga toxin, and trichosanthin, are RNA N-glycosidases that depurinate a specific adenine residue (A-4324 in rat 28S ribosomal RNA, rRNA) in the conserved α-sarcin/ricin loop (α-SRL) of rRNA.
Wei-Wei Shi, Amanda Nga-Sze Mak, Kam-Bo Wong, Pang-Chui Shaw   +3 more
doaj   +1 more source

Small-angle neutron scattering studies suggest the mechanism of BinAB protein internalization

IUCrJ, 2020
Small-angle neutron scattering (SANS) is one of the most widely used neutron-based approaches to study the solution structure of biological macromolecular systems.
Mahima Sharma, Vinod K. Aswal, Vinay Kumar, R. Chidambaram   +3 more
doaj   +1 more source

Detergent-protein and detergent-lipid interactions : implications for two-dimensional crystallization of membrane proteins and development of tools for high throughput crystallography [PDF]

, 2006
2.1 Scope of this Thesis This thesis represents an attempt to enlighten the role of the detergent in reconstitution and more specifically in two-dimensional (2D) crystallogenesis of membrane proteins. The construction of a tool for precise and routine
Kaufmann, Thomas Claudio
core   +1 more source

Study of the Interaction of Sorption and Catalytic Centers in Carboxypeptidase T by X-ray Analysis

Crystals, 2021
Carboxypeptidase T (CPT; EC 3.4.17.18) from Thermoactinomyces vulgaris is a distant homolog of the highly specific pancreatic carboxypeptidase B; but has a broad substrate specificity; the source of which remains unclear.
Valerij Akparov, Vladimir Timofeev, Inna Kuranova, Ilias Khaliullin   +3 more
doaj   +1 more source

Nanoflow electrospinning serial femtosecond crystallography

, 2012
An electrospun liquid microjet has been developed that delivers protein microcrystal suspensions at flow rates of 0.14-3.1 µl min(-1) to perform serial femtosecond crystallography (SFX) studies with X-ray lasers.
Zouni, Athina, Gildea, Richard J, Sokaras, Dimosthenis, Yachandra, Vittal K., Sierra, Raymond G, White, William E., Hattne, Johan, Glatzel, Pieter, Milathianaki, Despina, Weng, Tsu-Chien, Schafer, Donald W, Seibert, M. Marvin, Alonso-Mori, Roberto, Bergmann, Uwe, Kern, Jan, Messinger, Johannes, Sierra, Raymond G., Seibert, M Marvin,, Zwart, Petrus H, Messerschmidt, Marc M, Hampton, Christina Y., Grosse-Kunstleve, Ralf W, Grosse-Kunstleve, Ralf W., Adams, Paul D., Yachandra, Vittal K, Miahnahri, Alan, Schafer, Donald W., Sauter, Nicholas K., Sellberg, Jonas,, McQueen, Trevor A., Boutet, Sébastien, Starodub, Dmitri, Tran, Rosalie, Bogan, Michael J, Gildea, Richard J., Adams, Paul D, Zwart, Petrus H., Lassalle-Kaiser, Benedikt, Messerschmidt, Marc M., Bogan, Michael J., Messinger, Johannes,, Echols, Nathaniel, Hampton, Christina Y, Williams, Garth J, Sellberg, Jonas, Seibert, M Marvin, Laksmono, Hartawan, Yano, Junko, Gloeckner, Carina, McQueen, Trevor A, Loh, N Duane, Loh, N. Duane, Weng, Tsu Chien, Fry, Alan R, Fry, Alan R., Hellmich, Julia, Williams, Garth J., White, William E, Sauter, Nicholas K, Glöckner, Carina   +59 more
core   +1 more source