Results 11 to 20 of about 4,121,048 (281)
Infrared protein crystallography [PDF]
Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, 2011 We consider the application of infrared spectroscopy to protein crystals, with particular emphasis on exploiting molecular orientation through polarization measurements on oriented single crystals. Infrared microscopes enable transmission measurements on individual crystals using either thermal or nonthermal sources, and can accommodate flow cells ...
Sage, J. Timothy +5 more
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Emerging Topics in Protein Crystallography. [PDF]
Int J Mol SciProtein crystallography is the discipline concerned with the determination of the three-dimensional structure of biological macromolecules in a crystalline state [...]
Chen Z, Zanotti G.
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Fifteen years of the Protein Crystallography Station: the coming of age of macromolecular neutron crystallography [PDF]
IUCrJ, 2017 The Protein Crystallography Station (PCS), located at the Los Alamos Neutron Scattering Center (LANSCE), was the first macromolecular crystallography beamline to be built at a spallation neutron source.
Julian C.-H. Chen, Clifford J. Unkefer
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Exploring serial crystallography for drug discovery [PDF]
IUCrJStructure-based drug design is highly dependent on the availability of structures of the protein of interest in complex with lead compounds. Ideally, this information can be used to guide the chemical optimization of a compound into a pharmaceutical drug
A. Dunge +7 more
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Databases in Protein Crystallography [PDF]
Acta Crystallographica Section D Biological Crystallography, 1998 Applications of structural databases in the protein crystallographic structure determination process are reviewed, using mostly examples from work carried out by the authors. Four application areas are discussed: model building, model refinement, model validation and model analysis.
G J, Kleywegt, T A, Jones
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Application of differential scanning fluorimetry to X-ray protein crystallography. [PDF]
IUCrJX-ray crystallography remains a powerful technique for determining high-resolution protein structures; however, obtaining high-quality crystals is a significant bottleneck.
Sato Y, Senda T.
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Progress in protein crystallography. [PDF]
Protein Pept Lett, 2016 Macromolecular crystallography evolved enormously from the pioneering days, when structures were solved by "wizards" performing all complicated procedures almost by hand. In the current situation crystal structures of large systems can be often solved very effectively by various powerful automatic programs in days or hours, or even minutes.
Dauter Z, Wlodawer A.
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, 2022 Crystallography is an invaluable tool in materials science, solid state physics and protein science. Understanding crystallography requires grasping the powerful but abstract concept of reciprocal space.
Gustafson, Johan +9 more
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Macromolecular neutron crystallography at the Protein Crystallography Station (PCS) [PDF]
Acta Crystallographica Section D Biological Crystallography, 2010 The Protein Crystallography Station (PCS) at Los Alamos Neutron Science Center is a high-performance beamline that forms the core of a capability for neutron macromolecular structure and function determination. Neutron diffraction is a powerful technique for locating H atoms and can therefore provide unique information about how biological ...
Andrey, Kovalevsky +5 more
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High-throughput high-resolution cryo-electron crystallography [PDF]
, 2015 High-resolution structures of membrane and soluble proteins can be obtained by cryo-electron crystallography, given highly-ordered cryo-preparations of perfectly flat 2D crystals are available.
Scherer, Sebastian
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