Results 191 to 200 of about 1,856,978 (353)

Supplementary Information from Identification and Selective Degradation of Neopeptide-Containing Truncated Mutant Proteins in the Tumors with High Microsatellite Instability

, 2023
Won Kyu Kim, Misun Park, Minhee Park, Yun Ji Kim, Nara Shin, Hyun Ki Kim, Kwon Tae You, Hoguen Kim   +7 more
openalex   +1 more source

Hands‐on protocol for preparing water‐soluble fractions from agri‐food samples for NMR‐based metabolomics analysis

FEBS Open Bio, EarlyView.
This research protocol outlines a workflow for nuclear magnetic resonance (NMR)‐based metabolomics in the agri‐food sector. Using two case studies—strawberry leaves (solid matrix) and wine (liquid matrix)—it details the procedures for sample preparation, data acquisition, and processing.
Andrea Fernández‐Veloso, Jaime Hiniesta‐Valero, Alejandra Guerra‐Castellano, Miguel A. De la Rosa, Irene Díaz‐Moreno   +4 more
wiley   +1 more source

Participation of proteasome-ubiquitin protein degradation in autophagy and the activation of AMP-activated protein kinase

, 2015
Shaoning Jiang, Dae Won Park, Yong Gao, Saranya Ravi, Victor Darley‐Usmar, Edward Abraham, Jaroslaw W. Zmijewski   +6 more
openalex   +1 more source

Withdrawal: ERK and the F-box protein β TRCP target STAT1 for degradation. [PDF]

, 2018
Surinder M. Soond, Paul A. Townsend, Sean Barry, Richard A. Knight, David S. Latchman, Anastasis Stephanou   +5 more
openalex   +1 more source

Supplementary Figure 2 from Blockade of Fatty Acid Synthase Induces Ubiquitination and Degradation of Phosphoinositide-3-Kinase Signaling Proteins in Ovarian Cancer

, 2023
Katharina Tomek, R. B. Wagner, Franz Varga, Christian F. Singer, Heidrun Karlic, Thomas W. Grunt   +5 more
openalex   +1 more source

Establishment of a coculture system for Porphyromonas gingivalis and head and neck squamous cell carcinoma using spheroid culture and LATS inhibition

FEBS Open Bio, EarlyView.
We established a spheroid coculture system enabling viable Porphyromonas gingivalis–HNSCC interactions under normoxic conditions. Inhibition of LATS1/2 maintains tumor cells in an undifferentiated state, which may promote spheroid growth and create a more permissive environment for bacterial persistence.
Yurika Nakajima, Shogo Okazaki, Muneaki Tamura, Shuichi Sato, Kenichi Imai   +4 more
wiley   +1 more source

Orthogonal IMiD-Degron Pairs Induce Selective Protein Degradation in Cells. [PDF]

ACS Chem Biol
Brennan PJ, Saunders RE, Spanou M, Singleton SE, Serafini M, Sun L, Heger GP, Konopacka A, Beveridge RD, Taylor CC, DePaola P, Gordon L, Bunally SB, Saudemont A, Benowitz AB, Martinez-Fleites C, Schmitt DL, Damoiseaux R, Queisser MA, An H, Deane CM, Hann MM, Brayshaw LL, Conway SJ.   +23 more
europepmc   +1 more source

Influence of Nonprotein Nitrogen and Protein of Low Rumen Degradability on Nitrogen Flow and Utilization in Lactating Dairy Cows

, 1983
L. Kung, J.T. Huber, L.D. Satter
openalex   +1 more source

DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling

FEBS Open Bio, EarlyView.
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang, Jing Wang, De‐Hui Qian, Yang‐Fan Lv, Tian‐Le Cheng, Da‐Peng Wang, Jing Zhang, Ye Fan   +7 more
wiley   +1 more source

Proteolysis-targeting chimeras in cancer therapy: Targeted protein degradation for next-generation treatment. [PDF]

Cancer
Anaya YA, Barragan M, Bracho RP, Shaham SH, Bandyopadhyay D, George E, Nguyen D, Tripathi MK.   +7 more
europepmc   +1 more source