Results 161 to 170 of about 5,918,106 (339)

Perfluorooctanoic Acid Exposure Causes Macrophage Ammonia Retention and Induces Spontaneous Miscarriages

Advanced Science, EarlyView.
PFOA exposure induces pregnancy loss by promoting glutaminolysis, which further causes ammonia accumulation in macrophages. Cellular ammonia retention results in damage to mitochondria and lysosomes, which leads to cell death eventually. Impaired lysosomes also decrease the secretion of the Cathepsin B (CTSB), and attenuate macrophage infiltration and ...
Yongbo Zhao, Yijun Zhang, Hanyu Rao, Jiani Sun, Zhiyi Pan, Liping Jin, Yan Zhao   +6 more
wiley   +1 more source

Mass spectrometry detects folding intermediates populated during urea-induced protein denaturation. [PDF]

Chem Sci
Österlund N, Jordan JS, Renzi E, Szekeres GP, Pagel K.   +4 more
europepmc   +1 more source

Sensitive Label-Free Thermal Stability Assay for Protein Denaturation and Protein-Ligand Interaction Studies. [PDF]

Anal Chem, 2020
Vuorinen E, Valtonen S, Eskonen V, Kariniemi T, Jakovleva J, Kopra K, Härmä H.   +6 more
europepmc   +1 more source

Protein Denaturation and Roles of Denaturants

Seibutsu Butsuri, 2002
openaire   +2 more sources

Effect of heating strategies on whey protein denaturation--Revisited by liquid chromatography quadrupole time-of-flight mass spectrometry.

Journal of Dairy Science, 2016
Marije Akkerman, Valentin Rauh, M. Christensen, L. B. Johansen, M. Hammershøj, L. B. Larsen   +5 more
semanticscholar   +1 more source

YKT6 Promotes Bladder Cancer Progression by Stabilizing β‐catenin Through USP7‐Mediated Deubiquitination

Advanced Science, EarlyView.
The SNARE protein YKT6 is upregulated in bladder cancer (BLCA), correlating with poor prognosis. YKT6 promotes tumor proliferation and metastasis by activating Wnt/β‐catenin signaling. It recruits Ubiquitin‐Specific Peptidase 7 (USP7) to deubiquitinate and stabilize β‐catenin, enhancing its nuclear accumulation and driving oncogenic gene expression ...
Sheng Tu, Wenzhi Du, Yongwen Luo, Jiageng Shi, Tianyun Liu, Meng Ji, Kangping Xiong, Siming Chen, Fenfang Zhou, Mingxing Li, Jingtian Yu, Gang Wang, Lingao Ju, Yi Zhang, Yu Xiao, Xinghuan Wang, Kaiyu Qian   +16 more
wiley   +1 more source

Pressure Protein Denaturation Compared to Thermal and Chemical Unfolding: Analyses with Cooperative Models. [PDF]

J Phys Chem B
Seelig J, Seelig A.
europepmc   +1 more source

Engineered ice-binding protein (FfIBP) shows increased stability and resistance to thermal and chemical denaturation compared to the wildtype [PDF]

Yewon Nam, Dieu Linh Nguyen, Trang Hoang, Bogeun Kim, Jun Hyuck Lee, Hackwon Do   +5 more
openalex   +1 more source

Epstein‐Barr Virus Expressed Long Non‐Coding RNA (lncBARTs) Regulate EBV Latent Genome Replication

Advanced Science, EarlyView.
EBV produces abundant level of lncBARTs, which are essential for maintaining viral genome replication in EBV‐associated cancers. LncBARTs interact with a complex comprising BRD4, CTCF and viral protein EBNA1 at EBV oriP region. This interaction tethers oriP to host chromosomes, facilitating EBV episome replication.
Jiayan Liu, Dittman Lai‐Shun Chung, Larry Ka‐Yue Chow, Shuo Han, Wenkai Yi, Conor J. Cremin, Yingyin Liao, Pui Wang, Bobo Wing‐Yee Mok, Mingfang Ji, Jian Yan, Wei Dai, Honglin Chen   +12 more
wiley   +1 more source

The denaturation of proteins [PDF]

Biochemical Journal, 1932
Wilfrid James Loughlin, William Cudmore McCullagh Lewis   +1 more
openaire   +3 more sources