Results 141 to 150 of about 3,652,274 (296)

Atomic view of cosolute-induced protein denaturation probed by NMR solvent paramagnetic relaxation enhancement. [PDF]

Proc Natl Acad Sci U S A, 2021
Okuno Y, Yoo J, Schwieters CD, Best RB, Chung HS, Clore GM.   +5 more
europepmc   +1 more source

Use of the “Ru‐1O2‐Hydrazide” System Catalyzed by Metallic Ruthenium Complexes to Decipher the Interaction Between Microbes and Host Cancer Cells

Advanced Science, EarlyView.
ABSTRACT The dynamic interplay between bacteria and host cancer cells plays a critical role in tumor microenvironment modulation, bacterial pathogenesis, and potential oncotherapy applications. However, traditional methods often fail to capture transient or spatially restricted molecular interactions at the bacteria‐cancer cell interface.
Amin Sun, Kaihong Wang, Haifu Sun, Kemei Tao, Xiang Li, Xiuhua Zhao, Shuang Qiu   +6 more
wiley   +1 more source

Thermal Denaturation Kinetics of Whey Protein and Maltodextrin Mixture

, 2013
This chapter presents thermal denaturation studies of whey protein and maltodextrin mixture. Different compositions of whey protein–maltodextrin mixture were exposed to various temperature and holding time.
Jolius, Gimbun, M. M., Yusoff, J. Gimbun, M. M. Yusoff, Nuraini, Mohd Yusoff, N. M. Yusoff   +5 more
core   +1 more source

Noscapine hydrochloride (benzyl-isoquinoline alkaloid) effectively prevents protein denaturation through reduction of IL-6, NF-kB, COX-2, Prostaglandin-E2 in rheumatic rats. [PDF]

Saudi Pharm J, 2022
Akhter S, Irfan HM, Alamgeer, Ullah A, Jahan S, Roman M, Latif MB, Mustafa Z, Almutairi FM, Althobaiti YS.   +9 more
europepmc   +1 more source

Ovarian Cancer Diagnosis and Chemoresistance Prediction Model Based on cfRNA Molecular Signature

Advanced Science, EarlyView.
A deep learning model analyzes cfRNA profiles extracted from the blood of OVCA patients. This innovative approach distinguishes OVCA from healthy controls with high accuracy. Crucially, it reliably predicts patient response to chemotherapy (sensitive versus resistant subgroups).
Qinhao Guo, Yangyang Zhang, Yongcheng Jin, Siwei Deng, Yongqi Chen, Zheng Feng, Hao Wen, Liu Wang, Yilin Li, Fanghong Ou, Yong Shen, Haiming Li, Tianyao Zhou, Xingzhu Ju, Xiaohua Wu   +14 more
wiley   +1 more source

Robust and convenient analysis of protein thermal and chemical stability

, 2015
We present the software CDpal that is used to analyze thermal and chemical denaturation data to obtain information on protein stability. The software uses standard assumptions and equations applied to two-state and various types of three-state ...
Cecilia Andresen, Malin Lindqvist Appell, Markus Niklasson, Mårtensson, Lars-Göran,, Roth, Marie,, Lars‐Göran Mårtensson, Lundström, Patrik,, Zimdahl Kahlin, Anna,, Patrik Lundström, Niklasson, Markus,, Mårtensson, Lars-Göran, Helander, Sara,, Niklasson, Markus, Helander, Sara, Andrésen, Cecilia,, Lindqvist Appell, Malin,, Zimdahl Kahlin, Anna, Roth, Marie, Marie G.L. Roth, Lundström, Patrik, Sara Helander, Anna Zimdahl Kahlin, Andrésen, Cecilia, Lindqvist Appell, Malin   +23 more
core   +1 more source

Effect of Protein Denaturation Temperature on Rheological Properties of Baltic Herring (Clupea harengus membras) Muscle Tissue. [PDF]

Foods, 2021
Strzelczak A, Balejko J, Szymczak M, Witczak A.   +3 more
europepmc   +1 more source

Denaturation of Globular Proteins

Journal of Biological Chemistry, 1968
John R. Warren, Julius A. Gordon
openaire   +1 more source

Palmitoylation of PSD‐95 Orchestrates Learning‐Dependent Metaplasticity in the Amygdala and Fear Memory

Advanced Science, EarlyView.
This study reveals that fear learning specifically triggers PICK1/DHHC2‐dependent palmitoylation of PSD‐95 in the lateral amygdala. Fear conditioning induces the dissociation of DHHC5 from PSD‐95 and the association of PSD‐95 with DHHC2. DHHC2‐mediated palmitoylation of PSD‐95 is required for synaptic transmission and underlies fear learning–induced ...
Zu‐Cheng Shen, Yu‐Xuan Weng, Zhi‐Xuan Xia, Yue‐Ling Zhao, Qian‐Qian Ding, Si‐Ying Wang, Ting Cao, Xuan‐Ying Chen, Wu‐Cheng Tao, Shen Lin, Zhou Chen, Yi‐Xiao Luo   +11 more
wiley   +1 more source

Targeting the ATX‐LPA Axis Overcomes TKI Resistance and Immunosuppression in Renal Cell Carcinoma via Dual Inhibition of AKT/mTOR and TBK1/IRF3 Pathways

Advanced Science, EarlyView.
ABSTRACT Background Therapeutic resistance limits durable survival in advanced/metastatic renal cell carcinoma (RCC) treated with first‐line tyrosine kinase inhibitor (TKI) plus immune checkpoint inhibitor (ICI). We sought to define key resistance drivers and actionable targets.
Jinchen Luo, Hansen Lin, Haoqian Feng, Lei Tan, Xi Liu, Yong Huang, Junjie Cen, Jiajie Chen, Xinwei Zhou, Mingjie Lin, Wuyuan Liao, Zheyu Ai, Minyu Chen, Yinghan Wang, Wei Chen, Junhang Luo, Yanping Liang   +16 more
wiley   +1 more source