Results 121 to 130 of about 295,099 (303)

Robust and convenient analysis of protein thermal and chemical stability

, 2015
We present the software CDpal that is used to analyze thermal and chemical denaturation data to obtain information on protein stability. The software uses standard assumptions and equations applied to two-state and various types of three-state ...
Cecilia Andresen, Malin Lindqvist Appell, Markus Niklasson, Mårtensson, Lars-Göran,, Roth, Marie,, Lars‐Göran Mårtensson, Lundström, Patrik,, Zimdahl Kahlin, Anna,, Patrik Lundström, Niklasson, Markus,, Mårtensson, Lars-Göran, Helander, Sara,, Niklasson, Markus, Helander, Sara, Andrésen, Cecilia,, Lindqvist Appell, Malin,, Zimdahl Kahlin, Anna, Roth, Marie, Marie G.L. Roth, Lundström, Patrik, Sara Helander, Anna Zimdahl Kahlin, Andrésen, Cecilia, Lindqvist Appell, Malin   +23 more
core   +1 more source

Myofibrillar protein denaturation in freezing-thawing : Effect on thaw loss [PDF]

, 2020
The thesis aimed to study the effects and mechanisms of freezing-thawing treatments on myofibrillar protein denaturation and to explore the role of myofibrillar protein denaturation in causing the formation of thaw loss.
Zhang, Yuemei
core  

Domain rearrangement and denaturation in Ebola virus protein VP40

AIP Advances, 2018
The VP40 protein plays a critical role in coordinating the virion assembly, budding, and replication of the Ebola virus. Efforts have been made in recent years to understand various aspects of VP40 structure, dynamics, and function such as assembly of ...
Rudramani Pokhrel, Pornthep Sompornpisut, Prem Chapagain, Brian Olson, Bernard Gerstman, R. B. Pandey   +5 more
doaj   +1 more source

PET Imaging of Cardiac Inflammation in Viral Myocarditis Using a DPP4‐Targeted Probe

Advanced Science, EarlyView.
This study describes a DPP4‐targeted PET probe for imaging myocardial inflammation by selectively targeting activated immune cells. Derived from the clinically approved small‐molecule inhibitor linagliptin, the probe demonstrates favorable biodistribution with specific cardiac uptake in myocarditis.
Wanhao Gao, Wenzhu Hu, Du Tang, Xinxin Liu, Kun Yu, Lixia Feng, Minyu Liao, Wang Lin, Wenqiang Zhu, Sanjay Rajagopalan, Xiaoli Lan, Jixin Zhong, Dao Wen Wang, Dawei Jiang, Xiaoquan Rao   +14 more
wiley   +1 more source

Nanocellulose Alleviates Intrahepatic Cholestasis of Pregnancy via Gut Microbiota‐Mediated Bile Acid Homeostasis

Advanced Science, EarlyView.
Nanocellulose, derived from microcrystalline cellulose (MCC) through sulfuric acid hydrolysis or mechanical grinding to produce CNC or CNF, was tested in a rat ICP model. Particularly, CNF improved gut microbiota composition, reduced secondary bile acid metabolism, and restored bile acid homeostasis through modulation of the gut–liver axis.
Muhua Yu, Hongjie Dai, Xiaocui Zhong, Qibin Li, Hui Yuan, Yang Yang, Daiyong Huang, Lei Zhang, Rui Ran, Tian He, Yuanzhi Huang, Silas Villas‐Boas, Sergey Tumanov, Richard D. Cannon, Boris Novakovic, Richard Saffery, Yuhao Zhang, Xiaojing Dong, Ting‐Li Han   +18 more
wiley   +1 more source

Effect of enzymatic hydrolysates from sea cucumber ovum protein on fish storage quality and antifreeze activity

Food Science of Animal Products
Protein denaturation induced by ice crystal formation is the main contributor to the deterioration of fish quality during frozen storage. This study aims to extract hydrolysates capable of inhibiting protein denaturation from sea cucumber ovum protein ...
Zhe Xu, Shuang Guan, Zijin Qin, Xu Yan, Yikun Xu, Xiufang Dong, Yue Yu, Tingting Li   +7 more
doaj   +1 more source

A Microbial Lipid‐ATP Synthase Axis Fuels NK Cell Antitumor Activity

Advanced Science, EarlyView.
This study focuses on the mechanism by which gut microbiota‐derived outer membrane vesicles (OMVs) regulate NK cell antitumor activity. B. intestinalis is identified to decrease extra‐intestinal tumor growth via its OMVs enriched in sphingosine (SP).
Kaiyuan Yu, Xinyu Sun, Wanxia Ma, Jianming Yang, Xuan Sun, Lisong Zhang, Yumeng Liu, Tianshu Ren, Qi Wang, Jingyu Wang, Xiao Li, Xianping Peng, Liu Yang, Junqiang Lv, Zhi Yao, Zhi‐Song Zhang, Quan Wang   +16 more
wiley   +1 more source

Thermal Denaturation Kinetics of Whey Protein and Maltodextrin Mixture

, 2013
This chapter presents thermal denaturation studies of whey protein and maltodextrin mixture. Different compositions of whey protein–maltodextrin mixture were exposed to various temperature and holding time.
Jolius, Gimbun, M. M., Yusoff, J. Gimbun, M. M. Yusoff, Nuraini, Mohd Yusoff, N. M. Yusoff   +5 more
core   +1 more source

HNRNPU K181 Lactylation Drives Cervical Cancer Growth by Upregulating PHGDH and Reprogramming Serine Metabolism

Advanced Science, EarlyView.
Lactate in cervical cancer induces HNRNPU K181 lactylation, opposed by NAA50‐mediated acetylation and suppressed by Pazopanib. This lactylation enhances HNRNPU binding to PHGDH pre‐mRNA exon 1, maintaining exon 1‐containing transcripts and mRNA stability, thereby activating serine metabolism.
Chang Zhang, Qingfei Meng, Hui Jiao, Huixin Liu, Xiangchao Wang, Honglan Zhou, Yishu Wang   +6 more
wiley   +1 more source

A Review on Catalytic Nanostructured Electrodes for Wearable and Implantable Abiotic Glucose Fuel Cells

Advanced Science, EarlyView.
This review identifies current and future directions in abiotic nanostructured catalysts to develop reliable and sustainable glucose fuel cells to power the next generation of bioelectronic devices. ABSTRACT The global rise in incidence of chronic diseases has led to the demand for innovative solutions that help patients manage their conditions with ...
Asghar Niyazi, Hannah S. Leese, Benjamin Metcalfe, Mirella Di Lorenzo   +3 more
wiley   +1 more source