Results 131 to 140 of about 295,099 (303)
, 2011 For proteome research, "bottom-up" strategy is one of the most commonly used approaches, by which proteins are in turn denatured, reduced, alkylated, desaled and digested prior to multidimensional HPLC-ESI/MS/MS analysis. However, such a multistep sample
蒋好 +5 more
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Advanced Science, EarlyView.The ER's continuous tubular network is maintained by ER‐shaping proteins whose mutation or dysregulation contributes to neurodegenerative diseases. Here, we show that ER morphology sets the speed of Ca2+ store replenishment between firing events. Disrupting ER continuity slows intra‐ER Ca2+ redistribution from extracellular refill (SOCE) sites, driving
Valentina Davi +13 more
wiley +1 more source
On adsorption-induced denaturation of folded proteins. [PDF]
, 2001 In the absence of intramolecular long range interactions, the extended local conformation of a peptide chain is entropically favoured over compact ones, since the area of the Ramachandran basin of attraction is larger for the extended local ...
Fernández, Ariel, Ramsden, Jeremy J.
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Effect of rhuGSN on protein denaturation in vitro.
, 2015 Effect of rhuGSN on protein denaturation in vitro.
Devraj Parasar (783462) +7 more
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Advanced Science, EarlyView.This study elucidates that β‐elemene promotes cellular uptake of L. gasseri‐derived lactate by enhancing the membrane translocation of MCT1 in a CD147‐dependent manner. Intracellular lactate, through the lactylation of RBBP4 at the K26 site, recruits EP300 to the promoter regions of downstream genes (POLD1/POLD3), catalyzing H3K27ac modification.
Jiancheng He +10 more
wiley +1 more source
Formation and properties of whey protein fibrils
, 2011 Protein fibrils are threadlike aggregates that are about one molecule thick and more than thousand molecules long. Due to their threadlike structure they could potentially be used to form meat-like structures.
Kroes-Nijboer, A.
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Studies on the kinetics of protein denaturation under high pressure [PDF]
, 1960 The characteristics in the protein denaturation under pressure obtained by- the author up to date are summarized. Thermodynamic functions in the activation process of denaturation are calculated from the relations of absolute reaction rates using the ...
Suzuki, Keizo
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Advanced Science, EarlyView.Oligonucleotide‐based fluorescence in situ hybridization probes were developed in the model citrus species Citrus maxima. These probes were applied to comparative karyotyping across 14 species in the Rutaceae family. This analysis revealed chromosomal evolution in lineages that diverged from Citrus nearly 52 million years ago.
Li He +9 more
wiley +1 more source
Thermal dissection of lentil seedling amine oxidase domains by differential scanning calorimetry [PDF]
The relationships between the structural and energetic domains of lentil seedling amine oxidase (LSAO) were investigated using modifiers that target the active site and the carbohydrate moiety of the enzyme.
صبوری, علی اکبر +10 more
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Advanced Science, EarlyView.ABSTRACT Self‐healing materials represent a paradigm shift in designing functional biomedical devices for drug delivery, tissue regeneration, and 3D bioprinting. However, their clinical translation remains limited by challenges such as insufficient mechanical strength, potential cytotoxicity from chemical modifications, and complex activation ...
Ganjun Feng +15 more
wiley +1 more source