Results 261 to 270 of about 295,099 (303)

Protein Denaturation and Aggregation

Annals of the New York Academy of Sciences, 2006
Abstract: Protein aggregation is a prominent feature of many neurodegenerative diseases, such as Alzheimer's, Huntington's, and Parkinson's diseases, as well as spongiform encephalopathies and systemic amyloidoses. These diseases are sometimes called protein misfolding diseases, but the latter term begs the question of what is the “folded” state of ...
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THE FLUORESCENCE OF NATIVE, DENATURED AND REDUCED‐DENATURED PROTEINS*

Photochemistry and Photobiology, 1971
Abstract— (1) By excitation at 295 nm tryptophan fluorescence from 17 proteins was examined free of contributions from tyrosine. The tryptophan quantum yields for native proteins were both higher and lower than that of the free amino acid and spanned a 5‐fold range.
M. J. KRONMAN, L. G. HOLMES
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Measurement of Denaturation of Fish Protein

Nature, 1956
IT is well known that frozen fish alter in character during storage at sub-zero temperatures, becoming progressively tougher to eat, and exuding much fluid or ‘drip’ on thawing. The change proceeds more slowly the lower the temperature. There is a real need for an accurate objective method of measuring this deterioration, from the point of view of ...
J K, IRONSIDE, R M, LOVE
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Influence of micelles on protein's denaturation

International Journal of Biological Macromolecules, 2020
To evaluate the role of micelles for protein-surfactant interaction, we have studied the binding modes of serum albumin proteins (human (HSA) and rabbit (RSA)) with anionic-surfactant, sodium dodecyl sulfate (SDS) by using UV-visible, fluorescence, circular dichroism, fluorescence lifetime, atomic force microscopy (AFM) techniques.
Rachana, Srivastava, Md Sayem, Alam
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Nonideality and protein thermal denaturation

Biopolymers, 1999
We studied the thermal denaturation of eglin c by using CD spectropolarimetry and differential scanning calorimetry (DSC). At low protein concentrations, denaturation is consistent with the classical two-state model. At concentrations greater than several hundred microM, however, the calorimetric enthalpy and the midpoint transition temperature ...
J C, Waldner, S J, Lahr, M H, Edgell, G J, Pielak   +3 more
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Protein Denaturant Binding Polynomials

Journal of Protein Chemistry, 2002
We show how moments of the denaturant binding distribution function can be extracted from experimental data on the denaturation of a protein as a function of the concentration of denaturant and how in turn these moments can be used to construct the denaturant binding distribution function.
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Electroconformational Denaturation of Membrane Proteins

Annals of the New York Academy of Sciences, 2006
Abstract: Because of high electrical impedance of cell membrane, when living cells are exposed to an external electric field, the field‐induced voltage drops will mainly occur on the cell membrane. In addition to Joule heating damage and electroporation of the cell membrane, the electric field‐induced supraphysiological transmembrane potential may ...
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The Energy of Activation of Protein Denaturations

Science, 1937
The abnormally large values of the energy and the entropy of activation encountered in protein denaturations and enzyme destructions are illusory, since the customary method of calculating these quantities by the comparison of rates at constant p H alone is fallacious.
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Rotatory behavior of protein denaturation

Biochimica et Biophysica Acta, 1960
Abstract Reversible and irreversible denaturation processes were examined by rotatory dispersion. Samples of bovine serum albumin that were submitted to reversible denaturation by urea attained their original conformation after removal of the denaturing agent.
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Studies on Denaturation of Proteins XIII. A Theory of Denaturation†

1995
Publisher Summary Denaturation has been variously supposed to be depolymerization, anhydride formation or hydrolysis. It appears that the different theories do not refer to exactly the same phenomenon, but they can be reconciled if the difference between denaturation and coagulation is recognized.
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