Results 131 to 140 of about 86,419 (320)

Gaining extensive resistance against clubroot disease through the disruption of a susceptibility gene

Journal of Integrative Plant Biology, EarlyView.
This Commentary examines research by Wu et al. showing that β‐1,3‐glucan synthase‐like 5 (GSL5) functions as a key gene for susceptibility to clubroot in Brassica family members by suppressing immunity regulated by jasmonic acid. Inaction of GSL5 through genome editing provides broad‐spectrum resistance to clubroot.
Qibin Wu, Zhen Zeng, Daowen Wang, Zheng Qing Fu, Youxiong Que   +4 more
wiley   +1 more source

The Role of Oxidative Stress in Periodontitis

Journal of Periodontal Research, EarlyView.
Oxidative stress is involved in multiple chemical reactions that take place in different intracellular organelles: mitochondria, rough endoplasmic reticulum, peroxisomes, autophagy, and aging, and can be influenced by exogenous factors: nutrition, physical activity, psychological status, environmental conditions, microbiome, and drugs.
Pedro Bullon, Francesca Giampieri, Beatriz Bullon, Maurizio Battino   +3 more
wiley   +1 more source

Protein Disulfide Isomerase Modulates the Activation of Thyroid Hormone Receptors

Frontiers in Endocrinology, 2019
Thyroid hormone receptors (TRs) are responsible for mediating thyroid hormone (T3 and T4) actions at a cellular level. They belong to the nuclear receptor (NR) superfamily and execute their main functions inside the cell nuclei as hormone-regulated ...
Jessica L. O. Campos, Jessica L. O. Campos, Tabata R. Doratioto, Tabata R. Doratioto, Natalia B. Videira, Natalia B. Videira, Helder V. Ribeiro Filho, Helder V. Ribeiro Filho, Fernanda A. H. Batista, Juliana Fattori, Nathalia de C. Indolfo, Nathalia de C. Indolfo, Marcel Nakahira, Marcio C. Bajgelman, Aleksandra Cvoro, Francisco R. M. Laurindo, Paul Webb, Ana Carolina M. Figueira   +17 more
doaj   +1 more source

Protein disulphide isomerase-induced refolding of sonochemically prepared Ribonuclease A microspheres [PDF]

, 2012
The present communication describes for the first time the development of Ribonuclease A (RNase A) microspheres using the sonochemical method followed by an enzymatic treatment with protein disulphide isomerase (PDI).
Donelli, Ilaria, Fernandes, Margarida M., Ferreira, Helena, Freddi, G., Paulo, Artur Cavaco, Silva, Raquel   +5 more
core   +1 more source

A Fungal Cysteine‐Rich Protein SsSCP Activates Immune Responses and Confers Broad‐Spectrum Disease Resistance in Tomato

Plant Biotechnology Journal, EarlyView.
ABSTRACT Plant immune systems recognise pathogen‐derived molecular patterns to activate defence responses, yet the mechanisms underlying fungal pattern recognition in crops remain largely unclear. Here, we characterise the cysteine‐rich secretory protein SsSCP from the broad‐host‐range fungal pathogen Sclerotinia sclerotiorum as a potent elicitor of ...
Liyuan Zhang, Yuan Wang, Yuhang Liu, Jinwen Yang, Kaihao Zhang, Chengzhang Du, Jiajing Xiao, Ling Qing, Xinhua Sun   +8 more
wiley   +1 more source

Collagens - structure, function and biosynthesis. [PDF]

, 2003
The extracellular matrix represents a complex alloy of variable members of diverse protein families defining structural integrity and various physiological functions.
Aigner, T, Gelse, K, Poschl, E
core   +1 more source

Quiescin Sulfhydryl Oxidase‐Like 1 Positively Regulates Seed Dormancy in Rice

Plant Biotechnology Journal, EarlyView.
ABSTRACT Seed dormancy is an adaptive strategy that enables plants to survive adverse environmental conditions. In agricultural contexts, an optimal level of dormancy is essential: Insufficient dormancy can result in preharvest sprouting, while excessive dormancy may lead to uneven germination and poor stand establishment in subsequent crops.
Tengfei Ma, Qian Wang, Tao Wu, Qixian Hao, Yunshuai Huang, Changling Mou, Rong Miao, Jie Lan, Fulin Zhang, Ping Wang, Ziyan Zhu, Kunhao Li, Jiawei Song, Chen Hu, Yingying Chen, Boliang Lu, Yiwan Wu, Shijia Liu, Ling Jiang, Jianmin Wan   +19 more
wiley   +1 more source

Interactions between cell surface protein disulphide isomerase and S-nitrosoglutathione during nitric oxide delivery [PDF]

, 2007
In this study, we investigated the role of protein disulphide isomerase (PDI) in rapid metabolism of S-nitrosoglutathione (GSNO) and S-nitrosoalbumin (albSNO) and in NO delivery from these compounds into cells.
Askew, Burgess, C.M. Shah, Chen, Cooper, Crane, Crane, de Belder, Essex, Essex, Freedman, Gordge, Gordge, H.S. Chowdrey, Hogg, Hogg, Hogg, I.C. Locke, Jordan, Lahav, Lipton, Liu, Liu, M.P. Gordge, Ogura, O’Neill, Park, Park, Pfeiffer, Ramachandran, Richardson, Root, S.E. Bell, Shah, Simon, Sogo, Stamler, Walsh, Yan, Zai, Zeng, Zhang, Zhang   +42 more
core   +1 more source

Rapid expansion of the protein disulfide isomerase gene family facilitates the folding of venom peptides

Proceedings of the National Academy of Sciences of the United States of America, 2016
Significance The majority of secreted proteins contain disulfide bonds that provide structural stability in the extracellular environment. The formation of correct disulfide bonds is assisted by the enzyme protein disulfide isomerase (PDI). Most secreted
Helena Safavi-Hemami, Qing Li, R. L. Jackson, A. Song, Wouter Boomsma, P. Bandyopadhyay, Christian W. Gruber, A. Purcell, M. Yandell, B. Olivera, L. Ellgaard   +10 more
semanticscholar   +1 more source

Phylogenetic Relationship of Bombyx mori Protein Disulfide Isomerase

Zeitschrift für Naturforschung C, 2002
A cDNA that encodes protein disulfide isomerase was isolated from Bombyx mori (bPDI), in which an open reading frame of 494 amino acids contained two PDI-typical thioredoxin active sites of WCGHCK and an ER retention signal of the KDEL motif at its C-terminal. The bPDI protein shared less than 55% of the amino acid sequence homology with other reported
Tae Won, Goo, Eun Young, Yun, Jae-Sam, Hwang, Seok-Woo, Kang, Kwan-Hee, You, O Yu, Kwon   +5 more
openaire   +2 more sources