The Protein-disulfide Isomerase ERp57 Regulates the Steady-state Levels of the Prion Protein*
Background: ERp57 is a disulfide isomerase up-regulated in prion related-disorders, but its impact on PrP biology is unknown. Results: ERp57 gain- and loss-of-function can increase or reduce, respectively, PrP levels in neurons, both in cell culture and ...
Mauricio Torres+14 more
semanticscholar +1 more source
Background: Protein disulfide isomerase (PDI) family members are chaperones involved in apoptotic signaling through unclear mechanisms. Results: Pharmacological inhibition of PDI and PDIA3 activities reduces apoptotic signaling.
Guoping Zhao, Huayi Lu, Chi Li
semanticscholar +1 more source
Cloning, expression, purification and characterization of Leishmania tropica PDI-2 protein
In Leishmania species, protein disulfide isomerase (PDI) is an essential enzyme that catalyzes thiol-disulfide interchange. The present work describes the isolation, cloning, sequencing and expression of the pdI-2 gene.
Ali Dina+3 more
doaj +1 more source
Inhibition of a reductive function of the plasma membrane by bacitracin and antibodies against protein disulfide-isomerase. [PDF]
Richard Mandel+4 more
openalex +1 more source
Background Classic Philadelphia-negative myeloproliferative neoplasms (MPNs), such as polycythemia vera (PV), essential thrombocythemia (ET), and myelofibrosis (MF), are defined by the unregulated production of bone marrow components resulting from the ...
Marwa Salah Mohammed+7 more
doaj +1 more source
Glycosylation site binding protein and protein disulfide isomerase are identical and essential for cell viability in yeast. [PDF]
MaryLynne LaMantia+5 more
openalex +1 more source
Extracellular pools of intracellular molecular chaperones are increasingly evident. The peri/epicellular(pec) pool of the endoplasmic reticulum redox chaperone protein disulfide isomerase-A1(PDI) is involved in thrombosis and vascular remodeling, while ...
Thaís L.S. Araujo+2 more
doaj
A Common Binding Site on the Microsomal Triglyceride Transfer Protein for Apolipoprotein B and Protein Disulfide Isomerase [PDF]
Paul Bradbury+12 more
openalex +1 more source
Glutaredoxin Accelerates Glutathione-dependent Folding of Reduced Ribonuclease A Together with Protein Disulfide-isomerase [PDF]
Johanna Lundström-Ljung, Arne Holmgren
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Kinetic Analysis of the Mechanism and Specificity of Protein-disulfide Isomerase Using Fluorescence-quenched Peptides [PDF]
Vibeke Westphal+4 more
openalex +1 more source