Results 181 to 190 of about 16,988,925 (342)

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

FEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Aromatic ring flips reveal reshaping of protein dynamics in crystals and complexes. [PDF]

Nat Chem
Becker LM, Fu H, Tatman BP, Dreydoppel M, Kapitonova A, Balazs DM, Weininger U, Engilberge S, Chipot C, Schanda P.   +9 more
europepmc   +2 more sources

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

FEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

From Enhanced Sampling to Human-Readable Representations of Protein Dynamics. [PDF]

J Chem Theory Comput
Mondal S, Sauer MA, Heyden M.
europepmc   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

AI-Physics-Experiment Trinity for Integrated Protein Dynamics Modeling. [PDF]

Adv Sci (Weinh)
Shi C, Low M, Xiu P, Lindorff-Larsen K, Wang Y.   +4 more
europepmc   +1 more source

Normal mode analysis as a method to derive protein dynamics information from the Protein Data Bank

Biophysical Reviews, 2017
H. Wako, S. Endo
semanticscholar   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

Effect of Ergosterol on the Binding of KMP-11 with Phospholipid Membranes: Implications in Leishmaniasis

ACS Omega, 2019
Achinta Sannigrahi, Debasmita Mullick, Dwipanjan Sanyal, Sagnik Sen, Ujjwal Maulik, Krishnananda Chattopadhyay   +5 more
doaj   +1 more source

Solution Phase Protein Dynamics: Influences of ESI Buffers on Hydration. [PDF]

Anal Chem
Burningham E, Lantz C, Rider RL, Kuo ST, Yun SD, Laganowsky A, Russell DH.   +6 more
europepmc   +1 more source