CX3CL1 in Early Detection of Alzheimer's Disease: Plasma Dynamics Across Age and Disease Stages
ABSTRACT Backgrounds Alzheimer's disease (AD) is characterized by amyloid‐beta plaques, tau tangles, and neuroinflammation. C‐X3‐C motif chemokine ligand 1 (CX3CL1, also known as fractalkine), a neuroimmune chemokine implicated in AD pathogenesis, shows inconsistent alterations in plasma/serum across studies.
Ling Wang +6 more
wiley +1 more source
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Theoretical methods for studying protein motions have been outlined and some examples have been given. Simulation methods have shown that structural fluctuations in proteins cover a wide range in their magnitudes and time scales. Some indication of their biological role has been given, but the most important and interesting applications to protein ...
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