Results 221 to 230 of about 1,442,239 (292)

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source

Novel field-based approaches reveal wheat genotypic differences in nitrogen use efficiency and grain protein dynamics

Swarbreck SM, Ligeza A, Roques S, Kindred D, Sylvester-Bradley R, Griffiths H, Bentley AR.   +6 more
europepmc   +1 more source

The Evolution of the Acylation Mechanism in <i>β</i>-Lactamase and Rapid Protein Dynamics. [PDF]

ACS Catal
Frost CF, Antoniou D, Schwartz SD.
europepmc   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi, Lara Basovic, Christopher Michael McGraw   +2 more
wiley   +1 more source

Phospho-seq: integrated, multi-modal profiling of intracellular protein dynamics in single cells. [PDF]

Nat Commun
Blair JD, Hartman A, Zenk F, Wahle P, Brancati G, Dalgarno C, Treutlein B, Satija R.   +7 more
europepmc   +1 more source

Characterization of Clinical Phenotype to Glial Fibrillary Acidic Protein Concentrations in Alexander Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine the concentration of glial fibrillary acidic protein (GFAP) in cerebrospinal fluid (CSF) and plasma in Alexander disease (AxD) and whether GFAP levels are predictive of disease phenotypes. Methods CSF and plasma were collected (longitudinally when available) from AxD participants and non‐AxD controls.
Amy T. Waldman, Asako Takanohashi, Joshua Y. Joung, Geraldine W. Liu, Kaley Arnold, Amy Pizzino, Walter Faig, Sarah Woidill, Sona Narula, Adeline L. Vanderver   +9 more
wiley   +1 more source

Protein Dynamics at Different Timescales Unlock Access to Hidden Post-Translational Modification Sites

Lang B, Streit JO, Kriwacki RW, Christodoulou J, Babu MM.   +4 more
europepmc   +1 more source

Emerging approaches to investigating functional protein dynamics in modular redox enzymes: Nitric oxide synthase as a model system. [PDF]

J Biol Chem
Jiang T, Thielges MC, Feng C.
europepmc   +1 more source

Unraveling the Molecular Mechanisms of Glioma Recurrence: A Study Integrating Single‐Cell and Spatial Transcriptomics

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Glioma recurrence severely impacts patient prognosis, with current treatments showing limited efficacy. Traditional methods struggle to analyze recurrence mechanisms due to challenges in assessing tumor heterogeneity, spatial dynamics, and gene networks.
Lei Qiu, Yinjiao Fei, Jiaxuan Ding, Kexin Shi, Jinyan Luo, Yuchen Zhu, Xingjian Sun, Gefei Jiang, Yuandong Cao, Weilin Xu, Shu Zhou   +10 more
wiley   +1 more source

Single-Molecule Imaging of Integral Membrane Protein Dynamics and Function. [PDF]

Annu Rev Biophys
Modak A, Kilic Z, Chattrakun K, Terry DS, Kalathur RC, Blanchard SC.   +5 more
europepmc   +1 more source