Results 211 to 220 of about 827,705 (313)

Ultrafast Protein Dynamics Prior to Retinal Photoisomerization in Microbial Rhodopsins. [PDF]

J Phys Chem Lett
Tahara S, Kurihara R, Kojima K, Kuramochi H, Takeuchi S, Sudo Y, Tahara T.   +6 more
europepmc   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

Application of Anomaly Detection to Identify Important Features of Protein Dynamics. [PDF]

ACS Omega
Yamamori Y, Tomii K.
europepmc   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Genetic predisposition and the impact of missense genetic variants on the structural and functional protein dynamics in idiopathic pulmonary fibrosis. [PDF]

Lung India
Barney AM, Isaac B, Christopher DJ, Thangakunam B, Balaji J, Mohan VR, Christudass CS, Danda D, Danda S.   +8 more
europepmc   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Single-cell imaging of protein dynamics of paralogs reveals sources of gene retention. [PDF]

iScience
Dandage R, Papkov M, Greco BM, Pereira V, Fishman D, Friesen H, Wang K, Styles EB, Kraus O, Grys B, Zapata G, Lefebvre F, Bourque G, Boone C, Andrews BJ, Parts L, Kuzmin E.   +16 more
europepmc   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

FEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong, Yuhei Hosokawa, Lars Oliver Essen, Manuel Maestre‐Reyna   +3 more
wiley   +1 more source

Protein Dynamics [PDF]

, 2020
openaire   +1 more source

Protein Dynamics in Plant Immunity: Insights into Plant-Pest Interactions. [PDF]

Int J Mol Sci
Zhao Y, Wang Y.
europepmc   +1 more source