Rapidly evolving genes and stress adaptation of two desert poplars, Populus euphratica and P. pruinosa [PDF]
, 2013 Understanding which genes have evolved rapidly with the recent tree speciation in arid habitats can provide valuable insights into different adaptation mechanisms. We employed a comparative evolutionary analysis of expressed sequence tags (ESTs) from two
Penghui Xie (420345) +21 more
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Structural insights into the basis and evolution of interactions in multi-subunit protein assemblies. tryptophan synthase and titin FNIII-repeats [PDF]
, 2008 Cellular processes benefit from evolutionary shaping when optimized protein-protein interactions result in enhanced functionality. In fact, most cellular proteins are tightly embedded into biological networks that function following a modularity ...
Bucher, Rainer Michael
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Protein Evolution and Design [PDF]
Annual Review of Biochemistry, 2018 This article introduces the Protein Evolution and Design theme of the Annual Review of Biochemistry Volume 87.
openaire +2 more sources
Pix Proteins and the Evolution of Centrioles [PDF]
PLoS ONE, 2008 We have made a wide phylogenetic survey of Pix proteins, which are constituents of vertebrate centrioles in most eukaryotes. We have also surveyed the presence and structure of flagella or cilia and centrioles in these organisms, as far as is possible from published information.
Woodland, H. R., Fry, Andrew M.
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CHAPTER 1.1. Disulfide Bonds in Protein Folding and Stability [PDF]
, 2018 Disulfide bonds are unique among post-translational modifications, as they add covalent crosslinks to the polypeptide chain. Accordingly, they can exert pronounced effects on protein folding and stability. This is of particular importance for secreted or
Sub Cellular Protein Chemistry +7 more
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Sequence Motifs in MADS Transcription Factors Responsible for Specificity and Diversification of Protein-Protein Interaction [PDF]
, 2010 Protein sequences encompass tertiary structures and contain information about specific molecular interactions, which in turn determine biological functions of proteins.
Angenent, G.C. +23 more
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Universal Features in the Genome-level Evolution of Protein Domains [PDF]
, 2008 Protein domains are found on genomes with notable statistical distributions, which bear a high degree of similarity. Previous work has shown how these distributions can be accounted for by simple models, where the main ingredients are probabilities of ...
Bruno Bassetti +7 more
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Human Coronavirus: Envelope Protein Evolution
, 2021 Envelope protein of human coronavirus play significant role in an evolution and mutation of the virus life cycle. In the present research, the author evaluated amino acid sequences, its abundance and GC content of the genes that corresponds to envelope ...
Rutuja Ankulkar
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Evolution of signal multiplexing by 14-3-3-binding 2R-ohnologue protein families in the vertebrates [PDF]
, 2012 This work was supported by the UK Medical Research Council via a Developmental Pathway Funding Scheme award and a Research Councils UK fellowship in marine biology.14-3-3 proteins regulate cellular responses to stimuli by docking onto pairs of ...
Toth, Rachel +6 more
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Pediatric Idiopathic Multicentric Castleman Disease Is Often Severe But Responsive to Siltuximab
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Idiopathic multicentric Castleman disease (iMCD) is a potentially fatal immunologic disorder marked by widespread lymphadenopathy and inflammation. Siltuximab, an interleukin‐6 (IL‐6) inhibitor, is the only FDA‐approved treatment for adult patients with iMCD.
Bridget Austin +17 more
wiley +1 more source