Results 171 to 180 of about 6,771,465 (361)
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Glycopolymers stabilize protein folding and protein-protein interactions via enthalpic interactions. [PDF]
Richter SM, Brook N, Guseman AJ.
europepmc +1 more source
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
From Protein Folding to Precision Therapy: Surfactant Protein A in the Spotlight. [PDF]
Ziehr DR, Chivukula RR.
europepmc +1 more source
The Ribosome Modulates Nascent Protein Folding
Christian Kaiser +4 more
openalex +1 more source
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Resolving Molecular Interactions in Protein Folding Trajectories with NCIPLOT. [PDF]
Urriolabeitia A +3 more
europepmc +1 more source

