Results 191 to 200 of about 259,716 (267)

Navigating the landscape of protein folding and proteostasis: from molecular chaperones to therapeutic innovations. [PDF]

Signal Transduct Target Ther
Kuzu OF, Granerud LJT, Saatcioglu F.
europepmc   +1 more source

How phagocytic cells kill bacteria: Lessons from a professional killer

FEBS Open Bio, EarlyView.
How phagocytic cells ingest and kill bacteria has been studied for more than a century, but many questions remain unanswered. The study of the amoeba Dictyostelium discoideum brings new answers, and new questions. Professional phagocytic cells such as neutrophils and macrophages, as well as free‐living soil amoebae like Dictyostelium discoideum, employ
Otmane Lamrabet, Pierre Cosson
wiley   +1 more source

How the Extent of Protein Folding and Oligomerization Modulate Condensate Formation and Properties. [PDF]

J Phys Chem Lett
Edelstein I, Levy Y.
europepmc   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

The Arch from the Stones: Understanding Protein Folding Energy Landscapes via Bioinspired Collective Variables. [PDF]

J Phys Chem Lett
Rizzi V, Héritier M, Piasentin N, Aureli S, Gervasio FL.   +4 more
europepmc   +2 more sources

The Role of the Electronic Structure during Protein Folding through Electron Density-Based Quantum Chemical Descriptors. [PDF]

ACS Omega
Rocha-Santos A, Grillo IB, Aires Urquiza-Carvalho G, Rocha GB.   +3 more
europepmc   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

Unavailability of experimental 3D structural data on protein folding dynamics and necessity for a new generation of structure prediction methods in this context. [PDF]

Bioinformatics
Wells A, Newaz K, Morones J, Cheng J, Milenković T.   +4 more
europepmc   +1 more source

Effect of terahertz irradiation on DNA damage repair in living cells

FEBS Open Bio, EarlyView.
We investigated the effect of terahertz (THz) wave irradiation on DNA double‐strand break (DSB) repair in living cells. We found that THz irradiation enhanced DSB repair at specific frequencies, whereas heat treatment inhibited it, indicating that this effect is nonthermal and frequency‐specific.
Yuya Ueno, Shota Yamazaki, Hiromichi Hoshina, Masahiko Harata   +3 more
wiley   +1 more source

DR5 Disulfide Bonding Functions as a Sensor and Effector of Protein Folding Stress. [PDF]

Mol Cancer Res
Law ME, Dulloo ZM, Eggleston SR, Takacs GP, Alexandrow GM, Lee YI, Wang M, Hardy B, Su H, Forsyth B, Das P, Datta PK, Chiang CW, Sharma A, Kanumuri SRR, Guryanova OA, Harrison JK, Tirosh B, Castellano RK, Law BK.   +19 more
europepmc   +1 more source