Results 221 to 230 of about 6,845,089 (390)

The case for defined protein folding pathways

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2017
S. Englander, L. Mayne
semanticscholar   +1 more source

Decrypting cancer's spatial code: from single cells to tissue niches

open access: yesMolecular Oncology, EarlyView.
Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik   +4 more
wiley   +1 more source

G-quadruplexes catalyze protein folding by reshaping the energetic landscape. [PDF]

open access: yesProc Natl Acad Sci U S A
Huang Z, Ghosh K, Stull F, Horowitz S.
europepmc   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

open access: yesMolecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian   +10 more
wiley   +1 more source

Effect of Ergosterol on the Binding of KMP-11 with Phospholipid Membranes: Implications in Leishmaniasis

open access: yesACS Omega, 2019
Achinta Sannigrahi   +5 more
doaj   +1 more source

Protein folding: Funnel model revised. [PDF]

open access: yesComput Struct Biotechnol J
Roterman I, Slupina M, Konieczny L.
europepmc   +1 more source

Construction of hyperthermostable d‐allulose 3‐epimerase from Arthrobacter globiformis M30 using the sequence information from Arthrobacter psychrolactophilus

open access: yesFEBS Open Bio, EarlyView.
d‐Allulose can be produced from d‐fructose by d‐allulose 3‐epimerase. Based on sequence homology information, we successfully engineered thermostable mutants with the protein engineering method. By integrating positive mutations, we constructed an enzyme that exhibits hyperthermostability without a loss in the activity.
Kensaku Shimada   +3 more
wiley   +1 more source

Heat shock proteins in protein folding and reactivation. [PDF]

open access: yesVavilovskii Zhurnal Genet Selektsii
Malkeyeva D, Kiseleva EV, Fedorova SA.
europepmc   +1 more source

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