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Bulletin of Mathematical Biology, 1993
It is believed that the native folded three-dimensional conformation of a protein is its lowest free energy state, or one of its lowest. It is shown here that both a two- and three-dimensional mathematical model describing the folding process as a free energy minimization problem is NP-hard.
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It is believed that the native folded three-dimensional conformation of a protein is its lowest free energy state, or one of its lowest. It is shown here that both a two- and three-dimensional mathematical model describing the folding process as a free energy minimization problem is NP-hard.
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Heterogeneity in Protein Folding and Unfolding Reactions
Chemical Reviews, 2022Sandhya Bhatia, Jayant Udgaonkar
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Cryo-EM structures reveal multiple stages of bacterial outer membrane protein folding
Cell, 2022Matthew Thomas Doyle +2 more
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Glycosylation-directed quality control of protein folding
Nature Reviews Molecular Cell Biology, 2015Davis Ng
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Unfolded Proteins and Protein Folding Studied by NMR
Chemical Reviews, 2004H Jane Dyson, Peter Wright
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Single-Molecule Studies of Protein Folding with Optical Tweezers
Annual Review of Biochemistry, 2020Christian Kaiser +2 more
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