Results 231 to 240 of about 251,250 (306)

Day/night variations of myeloid and lymphoid cell subsets in the murine inguinal lymph node

FEBS Open Bio, EarlyView.
The circadian system is involved in the temporal regulation of the immune system. Our study reveals that two innate immune populations, NKT cells and neutrophils, predominate at the beginning of the day in healthy mice, highlighting how the time of day influences immune responses.
Paula M. Wagner, César G. Prucca, Lucia Boffelli, Virginia A. Piqueras, Silvia G. Correa, Mariana Maccioni, Mario E. Guido   +6 more
wiley   +1 more source

Prediction of Protein-Ligand Binding Affinities Using Atomic Surface Site Interaction Points. [PDF]

J Chem Inf Model
Zator KJ, Storer MC, Hunter CA.
europepmc   +1 more source

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

Chromosome-level genome assembly of a Chinese evergreen sweetgum (Liquidambar gracilipes, Altingiaceae). [PDF]

Sci Data
Ding S, Zhou F, Yang S, Li Y, Ma Y, Qiu Y.   +5 more
europepmc   +1 more source

Dietary nitrate and nitrite protect against doxorubicin‐induced cardiac fibrosis and oxidative protein damage in tumor‐bearing mice

FEBS Open Bio, EarlyView.
Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani, Xiaofei Chen, Nildris Cruz‐Diaz, Xuewei Zhu, Swati Basu, Daniel B. Kim‐Shapiro, David R. Soto‐Pantoja, Leslie B. Poole   +7 more
wiley   +1 more source

Reviewer #2 (Public review): Membrane-mimetic thermal proteome profiling (MM-TPP) toward mapping membrane protein–ligand dynamic interactions

openalex   +1 more source

Evolutionary dynamics of the chloroplast genome in Daphne (Thymelaeaceae): comparative analysis with related genera and insights into phylogenetics

FEBS Open Bio, EarlyView.
Comparative analysis of chloroplast genomes from 14 genera of Thymelaeaceae revealed variation in gene content, ranging from 128 to 142 genes, primarily influenced by IR expansion/contraction events and pseudogenization of ndhF, ndhI, and ndhG. Two large inversions were detected within the large single‐copy region, including a synapomorphic inversion ...
Abdullah, Hui Li, Rushan Yan, Chengyu Chen, Madiha Islam, Abdul Majid, Ibrar Ahmed, Parviz Heidari, Xiaoxuan Tian   +8 more
wiley   +1 more source

Structural Characterization of Protein-Nucleic Acid Complexes: An Overview of the Recent Innovation in the Analytic Methods. [PDF]

Int J Mol Sci
Bellone ML, Mensitieri F, Marmo E, Calabrese AN, Gaudino G, Izzo V, Dal Piaz F.   +6 more
europepmc   +1 more source

Mapping of host factors into the SARS-CoV-2 replication cycle reveals a direct interaction between entry factor perlecan and SARS-CoV-2 S protein.

Xin Yin (149454), Yuan Pu (3509042), Shuofeng Yuan (2827973), Lars Pache (562198), Christopher Churas (263984), Stuart Weston (611982), Laura Riva (3419369), Lacy M. Simons (12724489), William J. Cisneros (19648566), Thomas Clausen (273823), Grace Biddle (21533735), Simon Doss-Gollin (10983879), Meagan Deming (21533738), Paul D. De Jesus (11768000), Ha Na Kim (2198305), Daniel Fuentes (2651269), John M. Whitelock (8505543), Jeffrey D. Esko (216312), Megan S. Lord (6194639), Ignacio Mena (412719), Adolfo García-Sastre (51848), Judd F. Hultquist (12724492), Matthew B. Frieman (8905757), Trey Ideker (10055), Dexter Pratt (4351939), Laura Martin-Sancho (6475421), Sumit K. Chanda (11768006)   +26 more
openalex   +1 more source

Naked cuticle is essential for Drosophila wing development beyond Wingless signaling

FEBS Open Bio, EarlyView.
Naked cuticle (Nkd), a Wnt signaling inhibitor, assumes extensive roles in Drosophila wing development. Overexpressing Nkd causes smaller, crumpled wings, while also perturbing multiple signaling pathways and developmental genes. A specific region (R1S) is critical for Nkd's function as a signaling integrator, offering new insights for studying its ...
Rui Wang, Ping Wang
wiley   +1 more source