Results 241 to 250 of about 1,237,822 (372)

ChiPPI: a novel method for mapping chimeric protein–protein interactions uncovers selection principles of protein fusion events in cancer [PDF]

, 2017
Milana Frenkel‐Morgenstern, Alessandro Gorohovski, Somnath Tagore, Vaishnovi Sekar, Miguél Vázquez, Alfonso Valencia   +5 more
openalex   +1 more source

Association of high‐dose radioactive iodine therapy with PPM1D‐mutated clonal hematopoiesis in older individuals

Molecular Oncology, EarlyView.
In thyroid cancer patients, high‐dose (≥7.4 GBq) radioactive iodine therapy (RAIT) was associated with a higher prevalence of clonal hematopoiesis (variant allele frequency >2%) in individuals aged ≥50 years (OR = 2.44). In silico analyses showed that truncating PPM1D mutations conferred a selective advantage under these conditions.
Jaeryuk Kim, Sungwoo Bae, Jaeyong Choi, Sun‐Wha Im, Bukyoung Cha, Gyeongseo Jung, Sun Wook Cho, Eul‐Ju Seo, Young Ah Lee, Jin Chul Paeng, Young Joo Park, Jong‐Il Kim   +11 more
wiley   +1 more source

Cell Mapping Toolkit: an end-to-end pipeline for mapping subcellular organization. [PDF]

Bioinformatics
Lenkiewicz J, Churas C, Hu M, Qian G, Jain M, Levinson MA, Al Manir S, Qin Y, Fong D, Ono K, Chen J, Gao C, Pratt D, Parker JA, Clark T, Ideker T, Schaffer LV.   +16 more
europepmc   +1 more source

Mapping protein interactions by combining antibody affinity maturation and mass spectrometry

, 2011
Michael R. Dyson, Yong Zheng, Cunjie Zhang, Karen Colwill, Kritika Pershad, Brian K. Kay, Tony Pawson, John McCafferty   +7 more
openalex   +1 more source

PRIMA: a gene-centered, RNA-to-protein method for mapping RNA-protein interactions [PDF]

, 2017
Alex M. Tamburino, Ebru Kaymak, Shaleen Shrestha, Amy D. Holdorf, Seán Ryder, Albertha J.M. Walhout   +5 more
openalex   +1 more source

Small modifier, big decision: switching to SUMO mode adds weight to cancer stemness in mammary tumors

Molecular Oncology, EarlyView.
Inhibition of protein SUMOylation has been shown to block tumorigenesis; however, the specific mechanisms by which SUMOylation controls the tumor‐initiating capacities remain elusive. Li et al. describe the role of Etv1 SUMOylation in cancer stem cells using mouse models of mammary gland tumorigenesis.
Veronika Yevdokimova, Yannick D. Benoit
wiley   +1 more source

In vivo structure profiling reveals human cytosolic and mitochondrial tRNA structurome and interactome in response to stress. [PDF]

Nat Commun
Peña N, Hou Y, Watkins CP, Huang S, Zhang W, Katanski CD, Pan T.   +6 more
europepmc   +1 more source

Mapping protein interactions of sodium channel Na_V1.7 using epitope-tagged gene targeted mice [PDF]

, 2017
Alexandros H. Kanellopoulos, Jennifer Koenig, Honglei Huang, Martina Pyrski, Queensta Millet, Stéphane Lolignier, Toru Morohashi, Samuel J. Gossage, Maude Jay, John E. Linley, Georgios Baskozos, Benedikt M. Kessler, James J. Cox, Frank Zufall, John N. Wood, Jing Zhao   +15 more
openalex   +1 more source

Understanding and measuring mechanical signals in the tumor stroma

FEBS Open Bio, EarlyView.
This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz, Chiara Cimmino, Maurizio Ventre, Alessandra Cambi   +3 more
wiley   +1 more source

Development of a self-assembling multimeric Bann-RBD fusion protein in Pichia pastoris as a potential COVID-19 vaccine candidate. [PDF]

Sci Rep
Jumadila O, Fakhri MD, Darsono A, Puspasari F, Kurniasih SD, Masduki FF, Vidilaseris K, Ihsanawati I, Artarini A, Tan MI, Giri-Rachman EA, Natalia D.   +11 more
europepmc   +1 more source