Results 271 to 280 of about 6,367,317 (393)

Temporal Transcriptional Regulation of Human Neuronal Differentiation via Forward Programming

Advanced Science, EarlyView.
Single‐cell profiling of TF‐induced forward programming versus stepwise dual‐SMAD differentiation reveals that divergent trajectories set the pace of neurogenesis. OLIG TFs advance cell‐cycle exit via NOTCH modulation, while NEUROD2 later accelerates maturation. The study elucidates transcriptional mechanisms governing differentiation timing, providing
Lingling Zhu, Weiguang Wang, Jian Zhang, Lei Liu, Minpeng Huang, Lei Diao, Shuang Feng, Qiong Yang, Hao Qiu, Bing Pan, Renee A Reijo Pera, Ji Liu, Ninuo Xia, Fang Fang   +13 more
wiley   +1 more source

Ribosome rescue factor PELOTA modulates translation start site choice for C/EBPα protein isoforms. [PDF]

Life Sci Alliance
Fernandez SG, Ferguson L, Ingolia NT.
europepmc   +1 more source

Impact of Common Vitamin D-Binding Protein Isoforms on Supplemental Vitamin D3 and/or Calcium Effects on Colorectal Adenoma Recurrence Risk: A Secondary Analysis of a Randomized Clinical Trial.

JAMA Oncol, 2023
Gibbs DC, Barry EL, Fedirko V, Baron JA, Bostick RM.   +4 more
europepmc   +1 more source

Investigation of the functional roles of specific protein kinase C isoforms in 3T3-F442A adipocyte development and function.

, 1998
Iona M. Millar
openalex   +1 more source

Revealing Missing Human Protein Isoforms Based on Ab Initio Prediction, RNA-seq and Proteomics

, 2015
Zhiqiang Hu, Hamish S. Scott, Guangrong Qin, Guangyong Zheng, Xixia Chu, Lu Xie, David L. Adelson, Bergithe E Oftedal, Parvathy Venugopal, Milena Babic, Christopher N Hahn, Bing Zhang, Xiaojing Wang, Nan Li, Chaochun Wei   +14 more
openalex   +1 more source

Membrane‐bound annexin V isoforms (CaBP33 and CaBP37) and annexin VI in bovine tissues behave like integral membrane proteins [PDF]

, 1992
Roberta Bianchi, Ileana Giambanco, Paolo Ceccarelli, Grazia Pula, Rosario Donato   +4 more
openalex   +1 more source

Complex Alternative Cytoplasmic Protein Isoforms of the Kaposi's Sarcoma-Associated Herpesvirus Latency-Associated Nuclear Antigen 1 Generated through Noncanonical Translation Initiation

Journal of Virology, 2012
T. Toptan, Lídia Fonseca, H. Kwun, Yuan Chang, P. Moore   +4 more
semanticscholar   +1 more source

Subicular Astrocytes Govern Seizure‐Impaired Fear Memory

Advanced Science, EarlyView.
Astrocytes in dorsal subiculum act as a critical modulator of seizure‐associated cognitive dysfunction, operating through a Ca2+‐dependent adenosine‐linked astrocyte‐neuron signaling pathway that disrupts neuronal circuit homeostasis. This research highlights the potential of astrocyte‐targeted interventions as a therapeutic strategy, moving beyond the
Yuying Shao, Jing Xi, Yuhao Sun, Yulan Li, Zhisheng Li, Wangjialu Lu, Jialu Chen, Lin Yang, Fan Fei, Heming Cheng, Li Cheng, Cenglin Xu, Zhuo Huang, Vladimir Parpura, Yi Wang, Zhong Chen   +15 more
wiley   +1 more source

Uncovering a multitude of stage-specific splice variants and putative protein isoforms generated along mouse spermatogenesis. [PDF]

BMC Genomics
Romeo-Cardeillac C, Trovero MF, Radío S, Smircich P, Rodríguez-Casuriaga R, Geisinger A, Sotelo-Silveira J.   +6 more
europepmc   +1 more source

A specific ovarian tumor protein isoform is required for efficient differentiation of germ cells in Drosophila oogenesis. [PDF]

, 1992
Wayne R. Steinhauer, Laura J. Kalfayan
openalex   +1 more source