Results 271 to 280 of about 441,552 (301)

Isoform separation of proteins by mixed-mode chromatography

Protein Expression and Purification, 2015
Mixed-mode chromatography uses a multimodal functional resin, mainly composed of electrostatic and aromatic/hydrophobic groups. Here we have tested 2 mixed-mode resins, anion-exchange Capto adhere and cation-exchange Capto MMC, using 2 model proteins, i.e., an Fc-fusion etanercept, and bovine serum albumin (BSA). When etanercept was produced in Chinese
Tsutomu, Arakawa, Sean, Ponce, Glen, Young   +2 more
openaire   +2 more sources

Prediction of novel isoforms of the mouse Mpv17l protein

Genome, 2009
The Mpv17l protein has two isoforms, M-LPL and M-LPS, which both regulate the production of reactive oxygen species (ROS) and protect against mitochondrial oxidative stress and apoptosis. M-LPL is ubiquitously expressed, while M-LPS is expressed mostly in the kidney of aged animals.
Charalambos, Magoulas, Avin, Jasim, Luis, Lopez de Heredia   +2 more
openaire   +2 more sources

Enhanced protein isoform characterization

Nature Methods, 2022
openaire   +2 more sources

The Scrapie Fibril Protein and Its Cellular Isoform

1991
Proteins need help to fold and attain their functional conformation (Ellis and Hemmingsen 1989), and mechanisms have evolved to prevent the accumulation of misfolded protein aggregates within cells (Pelham 1988). These mechanisms fail to prevent the formation of protease-resistant, misfolded forms of PrP (ScPrP) during the development of scrapie and ...
J, Hope, J, Manson
openaire   +2 more sources

Absolute Quantitation of Protein Posttranslational Modification Isoform

2015
Mass spectrometry has been widely applied in characterization and quantification of proteins from complex biological samples. Because the numbers of absolute amounts of proteins are needed in construction of mathematical models for molecular systems of various biological phenotypes and phenomena, a number of quantitative proteomic methods have been ...
Yang, Zhu, Li, Ning
openaire   +3 more sources

Antibody Design for the Quantification of Photosynthetic Proteins and Their Isoforms

Antibodies are a valuable research tool, with uses including detection and quantification of specific proteins. By using peptide fragments to raise antibodies, they can be designed to differentiate between structurally similar proteins, or to bind conserved motifs in divergent proteins.
Bloemers, Duncan, Carmo-Silva, Elizabete
openaire   +2 more sources

A predicted novel protein isoform of HOXA9

Leukemia Research, 2019
Jo-Wai D, Wang, Gabrielle L, Gross, Erin R, Andrew, Amanda, Padovan, Aude M, Fahrer   +4 more
openaire   +2 more sources

Simultaneous Detection of Six Isoforms of Tau Protein in Human Cerebrospinal Fluid by Multidimensional Mass Spectrometry-Based Targeted Proteomics

Journal of Proteome Research, 2021
Wenjun Zhang, Yun Chen
exaly  

Scrapie isoform of scrapie-associated protein

Journal of the American Veterinary Medical Association, 1990
openaire   +2 more sources

Analysis of protein isoforms: Can we do it better?

Proteomics, 2012
MIROSLAVA Stastna
exaly