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Contractile protein isoforms in muscle development

Developmental Biology, 1992
The contractile proteins of skeletal muscle are often represented by families of very similar isoforms. Protein isoforms can result from the differential expression of multigene families or from multiple transcripts from a single gene via alternative splicing.
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Interactions and conversions of prion protein isoforms

2001
Publisher Summary The properties of amyloidogenic protease-resistant form (PrP-res) have failed attempts to determine its high resolution structure. Nonetheless, low resolution analyses have shown that PrP-res retains significant α-helical content, but has much higher β-sheet content than PrP C .
B, Caughey   +5 more
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The Immunodetection of the Abnormal Isoform of Prion Protein

The Histochemical Journal, 1999
Transmissible spongiform encephalopathies such as scrapie in sheep and goats, Creutzfeldt-Jakob disease in humans and bovine spongiform encephalopathy in cattle, are neurodegenerative disorders. A proposed causative agent for these diseases is an infectious protein, the so called 'prion'.
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Contractile Protein Isoforms

1987
All active cell movement originates in the interaction of only a few different classes of protein molecules. The major representatives are Actin and Tropomyosin, which can assemble into long and thin filamentous polymers, and Myosin, which can also aggregate to form thick filaments.
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Allergenicity of some isoforms of white sesame proteins

Clinical & Experimental Allergy, 2002
SummaryBackground Allergy to sesame seeds is often associated with particularly severe reactions, with a high risk of anaphylaxis. The increase in reports of allergic reactions to sesame is probably due to the growing use of sesame seeds or sesame oil in food.Objective To determine the molecular weights of the proteins in three variety of sesame seeds ...
S, Fremont   +6 more
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Isoform separation of proteins by mixed-mode chromatography

Protein Expression and Purification, 2015
Mixed-mode chromatography uses a multimodal functional resin, mainly composed of electrostatic and aromatic/hydrophobic groups. Here we have tested 2 mixed-mode resins, anion-exchange Capto adhere and cation-exchange Capto MMC, using 2 model proteins, i.e., an Fc-fusion etanercept, and bovine serum albumin (BSA). When etanercept was produced in Chinese
Tsutomu, Arakawa   +2 more
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Absolute Quantitation of Protein Posttranslational Modification Isoform

2015
Mass spectrometry has been widely applied in characterization and quantification of proteins from complex biological samples. Because the numbers of absolute amounts of proteins are needed in construction of mathematical models for molecular systems of various biological phenotypes and phenomena, a number of quantitative proteomic methods have been ...
Yang, Zhu, Li, Ning
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Signalling by protein kinase C isoforms in the heart

Molecular and Cellular Biochemistry, 1996
Understanding transmembrane signalling process is one of the major challenge of the decade. In most tissues, since Fisher and Krebs's discovery in the 1950's, protein phosphorylation has been widely recognized as a key event of this cellular function.
M, Pucéat, G, Vassort
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