Results 341 to 350 of about 6,367,317 (393)
Abstract 2690 Targeting SRSF6 RNA Isoform Regulation Using RNA Binding Protein Fused dCas13d
Tilda Carlelycke +2 more
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Drug design targeting active posttranslational modification protein isoforms
Medicinal research reviews (Print), 2020Modern drug design aims to discover novel lead compounds with attractable chemical profiles to enable further exploration of the intersection of chemical space and biological space.
Fanwang Meng +3 more
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Contractile protein isoforms in muscle development
Developmental Biology, 1992The contractile proteins of skeletal muscle are often represented by families of very similar isoforms. Protein isoforms can result from the differential expression of multigene families or from multiple transcripts from a single gene via alternative splicing.
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Factors affecting interactions between prion protein isoforms
Biochemical Society Transactions, 2002Interactions between normal, protease-sensitive prion protein (PrP-sen or PrPc) and its protease-resistant isoform (PrP-res or PrPsc) are critical in transmissible spongiform encephalopathy (TSE) diseases. To investigate the propagation of PrP-res between cells we tested whether PrP-res in scrapie brain microsomes can induce the conversion of PrP-sen ...
B, Caughey, G S, Baron
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Protein kinase C isoforms in human erythrocytes
Annals of Hematology, 2001Erythrocytes are the most abundant cells in blood and carry out the vital function of oxygen transport. These cells lack nuclei and do not synthesise new proteins. Their cellular responses are modulated entirely by post-translational modifications in existing proteins.
R B, Govekar, S M, Zingde
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Protein Kinase C (PKC) Isoforms in Drosophila
Journal of Biochemistry, 2002Six protein kinase C (PKC) genes are present in Drosophila, comprising two classical PKCs (PKC53E and eye-PKC), two novel PKCs (PKC98E and PKCdelta), an atypical PKC (DaPKC), and a PKC-related kinase. Loss of function alleles affecting DaPKC and eye-PKC are available and their mutant phenotypes have been characterized.
Bih-Hwa, Shieh +2 more
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1987
All active cell movement originates in the interaction of only a few different classes of protein molecules. The major representatives are Actin and Tropomyosin, which can assemble into long and thin filamentous polymers, and Myosin, which can also aggregate to form thick filaments.
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All active cell movement originates in the interaction of only a few different classes of protein molecules. The major representatives are Actin and Tropomyosin, which can assemble into long and thin filamentous polymers, and Myosin, which can also aggregate to form thick filaments.
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Protein Kinase C Isoform Diversity in Preconditioning
Journal of Surgical Research, 1997Protein kinase C (PKC) appears to be a common intracellular effector and signal collector during cardiac preconditioning; however, it remains unknown whether agonists that activate different PKC isoforms are also linked to select aspects of myocardial protection.
D R, Meldrum +7 more
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Isoform Specific Amyloid-β Protein Precursor Metabolism
Journal of Alzheimer's Disease, 2007Alzheimer's amyloid-β protein precursor (AβPP) can occur in different isoforms, among them AβPP751, which is the most abundant isoform in non-neuronal tissues, and AβPP695, often referred to as the neuronal isoform. However, few isoform-specific roles have been addressed.
Ana Gabriela, Henriques +5 more
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