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MICAL-1 isoforms, novel rab1 interacting proteins

Biochemical and Biophysical Research Communications, 2003
Rab1 GTPases participate in regulating the vesicular transport of ER-Golgi compartments. Recently, GM130, p115, and Golgin-84 were identified as effectors of the active conformation of rab1. Here, we describe a novel protein, MICAL-1b, a splice variant of the MICAL-1a protein.
Thomas, Weide   +3 more
openaire   +2 more sources

Absolute Quantitation of Protein Posttranslational Modification Isoform

2015
Mass spectrometry has been widely applied in characterization and quantification of proteins from complex biological samples. Because the numbers of absolute amounts of proteins are needed in construction of mathematical models for molecular systems of various biological phenotypes and phenomena, a number of quantitative proteomic methods have been ...
Yang, Zhu, Li, Ning
openaire   +3 more sources

Protein phosphatase 1 catalytic isoforms: specificity toward interacting proteins

Translational Research, 2014
The coordinated and reciprocal action of serine-threonine protein kinases and protein phosphatases produces transitory phosphorylation, a fundamental regulatory mechanism for many biological processes. Phosphoprotein phosphatase 1 (PPP1), a major serine-threonine phosphatase, in particular, is ubiquitously distributed and regulates a broad range of ...
Luís Korrodi-Gregório   +2 more
openaire   +2 more sources

Interactions and conversions of prion protein isoforms

2001
Publisher Summary The properties of amyloidogenic protease-resistant form (PrP-res) have failed attempts to determine its high resolution structure. Nonetheless, low resolution analyses have shown that PrP-res retains significant α-helical content, but has much higher β-sheet content than PrP C .
B, Caughey   +5 more
openaire   +2 more sources

SAA1 Protein Isoforms Induce Rheumatoid Arthritis

SSRN Electronic Journal, 2019
Background: Secondary amyloid A amyloidosis, a lethal complication, is induced when acute or chronic infection coexisted with over-secretion of the SAA1 protein and deposition of SAA1 in key internal organs. Previously, using the whole-exome sequencing method, we identified the novel deleterious mutation SAA1.2 in rheumatoid arthritis (RA) patients ...
Elaine Lai-Han Leung   +13 more
openaire   +1 more source

The contemporary management of cancers of the sinonasal tract in adults

Ca-A Cancer Journal for Clinicians, 2023
Rajat Thawani
exaly  

Highly accurate protein structure prediction with AlphaFold

Nature, 2021
John M Jumper   +2 more
exaly  

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