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Inhibition of protein kinase R suppresses HIV replication and integration in CD4 T cells. [PDF]

open access: yesJ Virus Erad
Pyburn J   +14 more
europepmc   +1 more source

Structural basis for amyloid fibril assembly by the master cell-signaling regulator receptor-interacting protein kinase 1. [PDF]

open access: yesNat Commun
Polonio P   +7 more
europepmc   +1 more source
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Protein kinases

Current Opinion in Structural Biology, 1994
The structures of four serine/threonine protein kinases have been determined recently. By comparing these structures with that of the cAMP-dependent protein kinase (cAPK), it is now possible to see how the activity of these regulatory enzymes is controlled. Low activity is maintained through the conformation of the phosphorylation lip, domain rotations,
E J, Goldsmith, M H, Cobb
openaire   +2 more sources

A-kinase anchoring proteins: protein kinase A and beyond

Current Opinion in Cell Biology, 2000
Compartmentalization of kinases and phosphatases is a key determinant in the specificity of second messenger mediated signaling events. Localization of the cAMP-dependent protein kinase (PKA) and other signaling enzymes is mediated by interaction with A-kinase anchoring proteins (AKAPs).
A S, Edwards, J D, Scott
openaire   +2 more sources

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