Results 241 to 250 of about 1,944,084 (333)

β2-Adrenergic Receptor Activates Extracellular Signal-regulated Kinases (ERKs) via the Small G Protein Rap1 and the Serine/Threonine Kinase B-Raf [PDF]

, 2000
John Schmitt, Philip A. Stork
openalex   +1 more source

Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence

Molecular Oncology, EarlyView.
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova, Dominika Maurencova, Barbora Salovska, Marek Kratky, Tomas Mracek, Zuzana Korandova, Alena Pecinova, Pavla Vasicova, David Rysanek, Ladislav Andera, Ivo Fabrik, Rudolf Kupcik, Pavel Kashmel, Pinky Sultana, Vojtech Tambor, Jiri Bartek, Josef Novak, Marie Vajrychova, Zdenek Hodny   +18 more
wiley   +1 more source

Substrate preference of protein kinase B isoforms can vary depending on the cell line. [PDF]

PLoS One
Palma MS, Perez SR, Husain A, Bhandari D.   +3 more
europepmc   +1 more source

The role of protein kinase B and mitogen-activated protein kinase in epidermal growth factor and tumor necrosis factor ?-mediated rat hepatocyte survival and apoptosis [PDF]

, 2000
Ruth Roberts, Neil H. James, Sabina Cosulich   +2 more
openalex   +1 more source

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

Molecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu, Katherine Eason, Suet‐Feung Chin, Paul A. W. Edwards, Raquel Manzano Garcia, Richard Moulange, Jia Wern Pan, Soo Hwang Teo, Sach Mukherjee, Maurizio Callari, Carlos Caldas, Stephen‐John Sammut, Oscar M. Rueda   +12 more
wiley   +1 more source

Electroacupuncture inhibits hippocampal oxidative stress and autophagy in sleep-deprived rats through the protein kinase B and mechanistic target of rapamycin signaling pathway. [PDF]

J Tradit Chin Med
Peng Z, Ying M, Meijun L, Di YU, Huiying L, Fuchun W, Xiaohong XU.   +6 more
europepmc   +1 more source

Protein kinase B (AKT) upregulation and Thy-1-α_vβ₃ integrin-induced phosphorylation of Connexin43 by activated AKT in astrogliosis. [PDF]

J Neuroinflammation, 2023
Pérez-Núñez R, Chamorro A, González MF, Contreras P, Artigas R, Corvalán AH, van Zundert B, Reyes C, Moya PR, Avalos AM, Schneider P, Quest AFG, Leyton L.   +12 more
europepmc   +1 more source

Semicochliodinol A and B: Inhibitors of HIV-1 Protease and EGF-R Protein Tyrosine Kinase Related to Asterriquinones Produced by the Fungus Chrysosporium merdarium.

, 1997
Andreas Fredenhagen, Frank Petersen, Marina Tintelnot‐Blomley, Johannes Rösel, Helmut Mett, Paul Hug   +5 more
openalex   +2 more sources

Inhibition of growth-factor-induced phosphorylation and activation of protein kinase B/Akt by atypical protein kinase C in breast cancer cells [PDF]

, 2000
Muling Mao, Xianjun Fang, Yiling Lu, Ruth LaPushin, Robert C. Bast, Gordon B. Mills   +5 more
openalex   +1 more source

CINs of the cytoplasm: dissecting dsRNA signaling in chromosomal instability

Molecular Oncology, EarlyView.
Micronuclei, formed during cell division in chromosomal instability settings, rupture and lead to the accumulation of immunogenic double‐stranded RNA in the cytoplasm, activating MAVS‐dependent interferon signaling and innate antitumor immunity.
Aglaia Skolariki, Rose L. Jady‐Clark, Eileen E. Parkes   +2 more
wiley   +1 more source