Results 271 to 280 of about 3,162,793 (373)

Protein kinase B (PKB; Akt); phosphoinositide 3-kinase (PI3K) [PDF]

Science-Business eXchange, 2010
openaire   +1 more source

Control of Cell Cycle Exit and Entry by Protein Kinase B-Regulated Forkhead Transcription Factors

Molecular and Cellular Biology, 2002
G. Kops, R. Medema, J. Glassford, M. Essers, P. Dijkers, P. Coffer, E. Lam, B. Burgering   +7 more
semanticscholar   +1 more source

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

FEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

Shenfushu granules attenuate diabetic kidney disease by inhibiting <i>PIK3R1</i>/protein kinase B/heparanase-mediated endothelial-mesenchymal transition. [PDF]

World J Diabetes
Yang XD, Ma SJ, Xiang DX, Yang YY.
europepmc   +1 more source

Normal insulin-dependent activation of Akt/protein kinase B, with diminished activation of phosphoinositide 3-kinase, in muscle in type 2 diabetes.

Journal of Clinical Investigation, 1999
Young-Bum Kim, S. Nikoulina, T. Ciaraldi, R. Henry, B. Kahn   +4 more
semanticscholar   +1 more source

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

FEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee, Ga Seul Lee, JinHan Kim, Kwang‐Hyun Park, Seong‐Ryung Go, Jeong Hee Moon, Eui‐Jeon Woo   +6 more
wiley   +1 more source

[Retracted] Isoflurane reduces pain and inhibits apoptosis of myocardial cells through the phosphoinositide 3‑kinase/protein kinase B signaling pathway in mice during cardiac surgery. [PDF]

Mol Med Rep
Pi Z, Lin H, Yang J.
europepmc   +1 more source

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

FEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia, Masahiro Kimura, Daisuke Kurimoto, Atsushi Sato   +3 more
wiley   +1 more source

Treatment strategies targeting the phosphoinositide 3-kinase/protein kinase B/mechanistic target of rapamycin pathway against triple-negative breast cancer. [PDF]

World J Clin Oncol
Ni CX, Xu JJ, Pang Y, Xu JJ.
europepmc   +1 more source

Follicle-Stimulating hormone (FSH) stimulates phosphorylation and activation of protein kinase B (PKB/Akt) and serum and glucocorticoid-lnduced kinase (Sgk): evidence for A kinase-independent signaling by FSH in granulosa cells.

Molecular Endocrinology, 2000
I. GONZALEZ-ROBAYNA, Allison E. Falender, S. Ochsner, G. Firestone, J. Richards   +4 more
semanticscholar   +1 more source