Results 181 to 190 of about 1,861,293 (359)

Activation of protein kinase C modulates the adenylate cyclase effector system of B-lymphocytes

, 1989
Erik C. Wiener, A. Scarpa
openalex   +1 more source

A synthetic peptide analog of the putative substrate‐binding motif activates protein kinase C [PDF]

, 1989
Colin M. House, Phillip J. Robinson, Bruce E. Kemp   +2 more
openalex   +1 more source

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

Molecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande, Marcela de Oliveira Silva, Mariana Bisarro dos Reis, Rodrigo de Oliveira Cavagna, Luciane Sussuchi, Icaro Alves Pinto, Natalia Zampieri Pontes, Rodrigo Sampaio Chiarantano, Flavio Augusto Ferreira da Silva, Pedro de Marchi, Letícia Ferro Leal, Rui M. Reis   +11 more
wiley   +1 more source

UCN-01 and UCN-02, new selective inhibitors of protein kinase C. II. Purification, physico-chemical properties, structural determination and biological activities.

, 1989
ISAMI TAKAHASHI, Yutaka Saitoh, Mayumi Yoshida, Hiroshi Sano, Hirofumi Nakano, Makoto Morimoto, Tatsuya Tamaoki   +6 more
openalex   +2 more sources

Protein kinase C negatively modulated by phorbol ester [PDF]

, 1986
Masaki Inagaki, Masatoshi Hagiwara, Masahiro Saitoh, Hiroyoshi Hidaka   +3 more
openalex   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Calphostins, novel and specific inhibitors of protein kinase C. II. Chemical structures.

, 1989
Takao Iida, Em KOBAYASHI, Mayumi Yoshida, Hiroshi Sano   +3 more
openalex   +2 more sources

Proteolytic activation of protein kinase C in the extracts of cells treated for a short time with phorbol ester [PDF]

, 1987
László Buday, János Seprődi, Gyöngyi Farkas, György Mészáros, Tibor Romhányi, Gábor Bánhegyi, József Mandl, F. Antoni, Anna F. Farago   +8 more
openalex   +1 more source

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source

Activation of protein kinase C induces differentiation in the human T-lymphoblastic cell line MOLT-3

, 1989
Yusuke Yamauchi, Kazuki Nagasawa, Takehito Mayumi, Takahiko Horiuchi, Yoshiyuki Niho   +4 more
openalex   +1 more source