Results 171 to 180 of about 1,266,408 (258)

Genomic and Transcriptomic Characterization of Protein Kinase C Fusion Melanocytic Neoplasms With Distinctive Hypopigmented Histomorphology: A Single-Institution Study. [PDF]

J Cutan Pathol
Li A, Umphress B, Dehner C, Jones R, Toral K, Warren S, Alomari AK.   +6 more
europepmc   +1 more source

Developing and Evaluating a Laboratory‐Based Frailty Index for the Prediction of Long‐Term Health Outcomes in Systemic Lupus Erythematosus

Arthritis Care &Research, EarlyView.
Objective We aimed to construct and evaluate the first laboratory‐based frailty index (FI‐Lab) for predicting adverse outcomes in systemic lupus erythematosus (SLE) and to compare its predictive ability to that of an existing clinical FI. Methods We used data from a single‐center prospective cohort of adult patients with SLE whose baseline visit ...
Grace Burns, Samuel D. Searle, Alexandra Legge   +2 more
wiley   +1 more source

Protein Kinase C [PDF]

, 2020
openaire   +1 more source

Pathogenic nsSNPs of protein kinase C-eta with hepatocellular carcinoma susceptibility. [PDF]

Cancer Cell Int
Hussain T, Badshah Y, Shabbir M, Abid F, Kamal GM, Fayyaz A, Trembley JH, Afsar T, Husain FM, Razak S.   +9 more
europepmc   +1 more source

Immunosuppressive Drug Use in Limited Systemic Sclerosis: An International Survey

Arthritis Care &Research, EarlyView.
Objective Current guidelines recommend immunosuppressive treatment for diffuse cutaneous systemic sclerosis but are less clear on their use in limited cutaneous systemic sclerosis (lcSSc) in the absence of internal organ complications. We conducted an international survey to understand current immunosuppressive drug prescribing patterns in lcSSc ...
Sabrina Hoa, Yicheng Mu, Marie Hudson, Janet Pope   +3 more
wiley   +1 more source

Modified lipoprotein-induced sFlt1 production in human placental trophoblasts is mediated by protein kinase C. [PDF]

Eur J Pharmacol
Chow RP, Zhao J, Li Y, Curtis TM, Lyons TJ, Yu JY.   +5 more
europepmc   +1 more source

Regulation of microtubule nucleation in glioblastoma cells by ARF GTPase-activating proteins GIT1 and GIT2 and protein kinase C. [PDF]

Cancer Cell Int
Sulimenko V, Dráberová E, Sládková V, Sulimenko T, Vosecká V, Skalli O, Dráber P.   +6 more
europepmc   +1 more source

β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations

Advanced Biology, Volume 9, Issue 3, March 2025.
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio, B. Spedicato, G. Corallo, A. Inguscio, M. Greco, D. Musarò, D. Vergara, A. F. Muro, G. De Sabbata, L. R. Soria, N. Brunetti Pierri, M. Maffia   +11 more
wiley   +1 more source

Protein kinase C epsilon activation improves early survival in an acute porcine model of controlled hemorrhage. [PDF]

Sci Rep
Simchoni M, Wagnert-Avraham L, Derazne E, Nachman D, Gershon Y, Cohen Levi E, Horesh A, Cohen Y, Nitecki M, Glick Y, Eisenkraft A, Suissa N, Twig G, Gertz SD, Saada A, Furer A.   +15 more
europepmc   +1 more source

Microenvironmental Reprogramming by 3D Anisotropic Cardiac Extracellular Matrix Induces Nuclear Remodeling and Epigenetic Maturation of Chemically Induced Cardiomyocytes

Advanced Functional Materials, EarlyView.
A 3D anisotropic hydrogel derived from heart extracellular matrix guides cytoskeletal alignment and nuclear remodeling in reprogrammed cardiomyocyte‐like cells. This study reveals how matrix alignment modulates nuclear envelope dynamics and chromatin state, triggering transcriptional and functional maturation.
Seung Ju Seo, Mi Jeong Lee, Hyun Wook Kang, Seonhee Byeon, Soo‐Kyoung Choi, Nakwon Choi, Seung‐Woo Cho, Yoonhee Jin   +7 more
wiley   +1 more source