Results 1 to 10 of about 97,124 (258)
PKC inhibitors reveal PKC isoforms involved in HIV latency reversal and immunomodulation [PDF]
Journal of VirologyThe reservoir of persistently latently infected cells is a major barrier to a cure for HIV infection. Protein kinase C (PKC) modulators can reverse HIV latency and could thus be useful “Kick” components in “Kick and Kill” approaches to a cure.
Thomas D. Zaikos +10 more
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Protein kinase C-λ drives third-degree burn-induced muscle wasting via STAT3-dependent catabolic pathways [PDF]
Frontiers in PharmacologyObjectiveSevere burn injury triggers profound skeletal muscle atrophy through incompletely understood molecular mechanisms. This study investigated the role of protein kinase C (PKC) isoforms in burn-induced muscle wasting and evaluated potential ...
Peilong Li, Xinzhuang Liu, Guobao Huang
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تأثیر 4 هفته تمرین هوازی بر سطوح Trk-B ، PKC و AKT در هیپوکمپ رتهای نر مبتلا به بیماری آلزایمر [PDF]
فیزیولوژی ورزشی, 2021 واکنشهای تخریبی ناشی از AB در CNS منجر به اختلال فاکتورهای نوروتروفیک می شود که ممکن است به نوبه خود توسعه پاتولوژی آمیلوئید را تسهیل کند. اخیراً آثار ورزش بر این عوامل مورد توجه قرار گرفته است، با اینحال درک چگونگی اثر آن نیاز به بررسی بیشتر دارد ...
اصلان خدامرادی +2 more
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A PKC-based security architecture for WSN [PDF]
MATEC Web of Conferences, 2020 It is an important challenge to find out suitable cryptography for WSN due to limitations of energy, computation capability and storage resources. Considering this sensor feature on limitations of resources, a security architecture based-on public key ...
Yao Jianbo, Yang Chaoqiong
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Phosphorylation of the amino-terminus of the AGC kinase Gad8 prevents its interaction with TORC2 [PDF]
Open Biology, 2016 Cell proliferation, metabolism, migration and survival are coordinated through the tight control of two target of rapamycin (TOR) kinase complexes: TORC1 and TORC2.
Wei Du +3 more
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Journal of Cell Science, 2004 The protein kinase C (PKC) family is represented in all eukaryotes and in Homo sapiens comprises the related PKCα through PKCι gene products ([Dempsey et al., 2000][1]). The kinase domains are closely related, as illustrated in the dendrogram, and form part of the AGC kinase superfamily ...
Parker, P J, Murray-Rust, J
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Insights into Activation Mechanisms of Store-Operated TRPC1 Channels in Vascular Smooth Muscle
Cells, 2020 In vascular smooth muscle cells (VMSCs), the stimulation of store-operated channels (SOCs) mediate Ca2+ influx pathways which regulate important cellular functions including contraction, proliferation, migration, and growth that are associated with the ...
Miguel A. S. Martín-Aragón Baudel +3 more
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Protein Kinase C Life Cycle: Explained Through Systems Biology Approach
Frontiers in Physiology, 2022 Protein kinase C (PKC) enzymes are a family of kinases that mediate signal transduction originating at the cell surface. Most cell membranes can contain functional PKC enzymes.
Naveed Aslam, Farah Alvi, Farah Alvi
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Biomolecules, 2020 Acute hypertension produced by methamphetamine (MA) is well known, mainly by the enhancement of catecholamine release from sympathetic terminals. However, the central pressor mechanism of the blood-brain-barrier-penetrating molecule remains unclear.
Chih-Chia Lai +4 more
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Cadmium induces CCL2 production in glioblastoma cells via activation of MAPK, PI3K, and PKC pathways
Journal of Immunotoxicology, 2020 Cadmium (Cd) is accumulated in human astrocytes and induces the production of interleukin (IL)-6 and IL-8. Astrocytes are one of the major sources of chemokine C–C motif ligand 2 (CCL2; known as monocyte chemoattractant protein-1 [MCP-1]), in the brain ...
Thitima Kasemsuk +4 more
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