Results 31 to 40 of about 1,136,073 (218)
Protein kinase C phosphomimetics alter thin filament Ca2+ binding properties. [PDF]
PLoS ONE, 2014 Adrenergic stimulation modulates cardiac function by altering the phosphorylation status of several cardiac proteins. The Troponin complex, which is the Ca(2+) sensor for cardiac contraction, is a hot spot for adrenergic phosphorylation. While the effect
Bin Liu +3 more
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Calcium Stimulates Self-Assembly of Protein Kinase C α In Vitro. [PDF]
PLoS ONE, 2016 Protein kinase C α (PKCα) is a nodal regulator in several intracellular signaling networks. PKCα is composed of modular domains that interact with each other to dynamically regulate spatial-temporal function.
Carter J Swanson +6 more
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Phosphorylation of Hepatitis C Virus Core Protein by Protein Kinase A and Protein Kinase C
Virology, 2002 Hepatitis C virus (HCV) core protein can form capsid-like particles and is believed to be the viral capsid protein. Besides its structural functions, this protein is also known to possess multiple regulatory functions. In this article, we have studied the possible phosphorylation of HCV core protein in two different human liver-derived cell lines Huh7 ...
Jing-Hsiung Ou, Wen Lu
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Interaction of protein kinase C ζ with ZIP, a novel protein kinase C-binding protein [PDF]
Proceedings of the National Academy of Sciences, 1997 The atypical protein kinase C (PKC) member PKC-ζ has been implicated in several signal transduction pathways regulating differentiation, proliferation or apoptosis of mammalian cells. We report here the identification of a cytoplasmic and membrane-associated protein that we name zeta-interacting protein (ZIP) and that interacts with the ...
Ferdi Grawe +3 more
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PLoS ONE, 2020 Adenoviruses cause upper respiratory infections, conjunctivitis, keratitis, and gastrointestinal illness. These can be fatal in immunocompromised individuals.
Alice Liu +4 more
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Effects of Newly Synthesized DCP-LA-Phospholipids on Protein Kinase C and Protein Phosphatases
Cellular Physiology and Biochemistry, 2013 Background/Aims: The linoleic acid derivative DCP-LA selectively activates PKCε and inhibits protein phosphatase 1 (PP1). In the present study, we have newly synthesized phosphatidyl-ethanolamine, -serine, -choline, and -inositol containing DCP-LA at the
Takeshi Kanno +5 more
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Activation of cGMP-dependent Protein Kinase by Protein Kinase C [PDF]
Journal of Biological Chemistry, 2003 The cGMP-dependent protein kinases (PKG) are emerging as important components of mainstream signal transduction pathways. Nitric oxide-induced cGMP formation by stimulation of soluble guanylate cyclase is generally accepted as being the most widespread mechanism underlying PKG activation.
Nickolai O. Dulin +4 more
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Inhibition of protein kinase C by resveratrol
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 2003 Evidence is emerging that resveratrol (RV), a polyphenolic phytoaxelin present in dietary sources including red wine, may protect against atherosclerosis and cardiovascular disease by enhancing the integrity of the endothelium. In this study, the possibility that such beneficial effects of RV may arise from a modulation of protein kinase C (PKC ...
Anthony C. Cook +4 more
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Tumor Biology, 2017 Tumor-associated macrophages are key regulators of the complex interplay between tumor and tumor microenvironment. M2 Macrophages, one type of tumor-associated macrophages, are involved in prostate cancer growth and progression. Protein kinase C zeta has
Hui-hui Fan +6 more
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eLife, 2017 Influenza virus expresses transcripts early in infection and transitions towards genome replication at later time points. This process requires de novo assembly of the viral replication machinery, large ribonucleoprotein complexes (RNPs) composed of the ...
Arindam Mondal +8 more
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