Results 41 to 50 of about 1,266,309 (159)

Influenza virus recruits host protein kinase C to control assembly and activity of its replication machinery

eLife, 2017
Influenza virus expresses transcripts early in infection and transitions towards genome replication at later time points. This process requires de novo assembly of the viral replication machinery, large ribonucleoprotein complexes (RNPs) composed of the ...
Arindam Mondal, Anthony R Dawson, Gregory K Potts, Elyse C Freiberger, Steven F Baker, Lindsey A Moser, Kristen A Bernard, Joshua J Coon, Andrew Mehle   +8 more
doaj   +1 more source

ORM Promotes Skeletal Muscle Glycogen Accumulation via CCR5-Activated AMPK Pathway in Mice

Frontiers in Pharmacology, 2016
We found previously that acute phase protein orosomucoid reacts to fatigue and activates C-C chemokine receptor type 5 to increase muscle glycogen storage and enhance muscle endurance (Lei et al., 2016). To explore the underlying molecular mechanisms, we
Zhen Qin, Jing-Jing Wan, Yang Sun, Peng-Yuan Wang, Ding-Feng Su, Hong Lei, Xia Liu   +6 more
doaj   +1 more source

Cell membrane disruption stimulates cAMP and Ca2+ signaling to potentiate cell membrane resealing in neighboring cells

Biology Open, 2017
Disruption of cellular plasma membranes is a common event in many animal tissues, and the membranes are usually rapidly resealed. Moreover, repeated membrane disruptions within a single cell reseal faster than the initial wound in a protein kinase A (PKA)
Tatsuru Togo
doaj   +1 more source

Dephosphorylation specificities of protein phosphatase for cardiac troponin I, troponin T, and sites within troponin T

International Journal of Biological Sciences, 2006
Protein dephosphorylation by protein phosphatase 1 (PP1), acting in concert with protein kinase C (PKC) and protein kinase A (PKA), is a pivotal regulatory mechanism of protein phosphorylation.
doaj  

The Role of Protein Kinases in Antigen-activation of Peripheral Blood Mononuclear Cells of Schistosoma mansoni Infected Individuals

Memorias do Instituto Oswaldo Cruz, 1997
T cell recognition of antigens displayed on the surface of antigen presenting cell results in rapid activation of protein tyrosine kinases and kinase C.
Almeida Célia A, Goes Alfredo M
doaj  

37LRP induces invasion in hypoxic lung adenocarcinoma cancer cells A549 through the JNK/ERK/c-Jun signaling cascade

Tumor Biology, 2017
We previously reported that 37-kDa laminin receptor precursor involved in metastasis of lung adenocarcinoma cancer cells. In this study, we further revealed that hypoxia induced 37-kDa laminin receptor precursor expression and activation of extracellular
Yongan Zhou, Yafang Wang, Zhengwei Zhao, Yanxia Wang, Ning Zhang, Helong Zhang, Lili Liu   +6 more
doaj   +1 more source

Tamoxifen suppresses paclitaxel-, vincristine-, and bortezomib-induced neuropathy via inhibition of the protein kinase C/extracellular signal-regulated kinase pathway

Tumor Biology, 2018
Chemotherapy-induced neuropathy is a highly problematic, dose-limiting effect of potentially curative regimens of cancer chemotherapy. When neuropathic pain is severe, patients often either switch to less-effective chemotherapy agents or choose to ...
Masanobu Tsubaki, Tomoya Takeda, Mikihiro Matsumoto, Natsuki Kato, Shota Yasuhara, Yu-ichi Koumoto, Motohiro Imano, Takao Satou, Shozo Nishida   +8 more
doaj   +1 more source

Activated Protein C Induces Endoplasmic Reticulum Stress and Attenuates Lipopolysaccharide-Induced Apoptosis Mediated by Glycogen Synthase Kinase-3β

Mediators of Inflammation, 2012
This study investigated the relationship between antiapoptotic activities induced by activated protein C and endoplasmic reticulum stress. In this study, it was observed that activated protein C elicited a rise in glucose-regulated protein 78 and ...
Liang Luo, Tangfeng Lv, Qian Wang, Ting Zhang, Xiaoling Gu, Feng Xu, Yong Song   +6 more
doaj   +1 more source

The inhibitory effect of small interference RNA protein kinase C-alpha on the experimental proliferative vitreoretinopathy induced by dispase in mice

International Journal of Nanomedicine, 2013
Qianying Gao,1 Wencong Wang,1 Yuqing Lan,2 Xiaoqing Chen,1 Wei Yang,1 Yongguang Yuan,1 Juan Tan,1 Yao Zong,1 Zhaoxin Jiang1 1State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, People's Republic of ...
Gao Q, Wang W, Lan Y, Chen X, Yang W, Yuan Y, Tan J, Zong Y, Jiang Z   +8 more
doaj  

FK506 and protein kinase C [PDF]

Nature, 1991
M, Tropschug, R, Hofmann
openaire   +2 more sources