Results 241 to 250 of about 2,078,021 (401)

Spermine inhibits the phosphorylation of the 11,000- and 10,000-dalton nuclear proteins catalyzed by nuclear protein kinase NI in NB-15 mouse neuroblastoma cells.

, 1986
Rama Shanker Verma, Kuang Yu Chen
openalex   +1 more source

Ro 31‐8220 suppresses bladder cancer progression via enhancing autophagy in vitro and in vivo

FEBS Open Bio, EarlyView.
The pan‐protein kinase C inhibitor Ro‐31‐8220 demonstrates potent anti‐bladder cancer effects both in vitro and in vivo by suppressing migration/invasion, inducing apoptosis and crucially activating autophagy, where blocking autophagy with chloroquine reduces its cell‐killing efficacy, suggesting its promise as a novel therapeutic candidate requiring ...
Shengjun Fu, Yan Tao, Shan Wu, Yuwen Gong, Youli Zhao, Shaomin Niu, Hui Cheng, You Mu, Na Xu, Ying Wang, Jianzhong Lu, Shanhui Liu, Lanlan Li   +12 more
wiley   +1 more source

Novel Protein Kinase Inhibitors: SMART Drug Design Technology

BioTechniques, 2003
Tomi K. Sawyer, Regine S. Bohacek, Chester A. Metcalf III, William C. Shakespeare, Yihan Wang, Raji Sundaramoorthi, Terence Keenan, Surinder Narula, Manfred Weigele, David C. Dalgarno   +9 more
doaj   +1 more source

Updated analysis of the prescription and evaluation of protein kinase inhibitors for oncology in Germany. [PDF]

Naunyn Schmiedebergs Arch Pharmacol
Obst CS, Seifert R.
europepmc   +1 more source

Drug Repurposing and De Novo Drug Discovery of Protein Kinase Inhibitors as New Drugs against Schistosomiasis. [PDF]

Molecules, 2022
Pereira Moreira B, Weber MHW, Haeberlein S, Mokosch AS, Spengler B, Grevelding CG, Falcone FH.   +6 more
europepmc   +1 more source

Vinblastine accumulation induced by protein kinase inhibitors in rat ascites hepatoma AH66 cells

, 1989
Shinya Wakusawa, Ken‐ichi Miyamoto, Ryozo Koshiura, Hiroyoshi Hidaka   +3 more
openalex   +1 more source

High LRIG1 expression predicts lymph node metastasis in patients with uterine cervical cancer

FEBS Open Bio, EarlyView.
Lymph node status is crucial in determining treatment for women with early‐stage cervical cancer. We demonstrate that high LRIG1 protein expression in primary tumors can predict lymph node metastases. Our findings support further investigation of LRIG1 as a biomarker to improve staging accuracy and guide treatment decisions in cervical cancer patients.
Pernilla Israelsson, Lisa Lif, Husam Oda, Alexandra Lorenzzi de Melo, David Lindquist, Håkan Hedman   +5 more
wiley   +1 more source

Design, Synthesis, and Cytotoxicity Evaluation of Novel Indolin-2-One Based Molecules on Hepatocellular Carcinoma HepG2 Cells as Protein Kinase Inhibitors. [PDF]

Molecules
Kandeel MM, AbdElhameid MK, Adel M, Al-Shorbagy MY, Negmeldin AT.   +4 more
europepmc   +1 more source

Oncotherapeutic Protein Kinase Inhibitors Associated With Pro-Arrhythmic Liability. [PDF]

JACC CardioOncol, 2021
Ye JZ, Hansen FB, Mills RW, Lundby A.
europepmc   +1 more source

Calcium-dependent protein kinases and their selective inhibitors

, 1987
Satoshi Matsushima, Masahiro Saitoh, Tomohiko Ishikawa, Hiroyoshi Hidaka   +3 more
openalex   +1 more source