Results 161 to 170 of about 875,741 (363)

A Retroviral-Derived Immunosuppressive Peptide Activates Mitogen-Activated Protein Kinases [PDF]

, 2001
Akihisa Takahashi, Noorbibi K. Day, Voravich Luangwedchakarn, Robert A. Good, Soichi Haraguchi   +4 more
openalex   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Brassinosteroid signalling [PDF]

, 2020
Kim, Eun-Ji, Russinova, Eugenia
core   +2 more sources

Cloning and Characterization of Cell Adhesion Kinase β, a Novel Protein-tyrosine Kinase of the Focal Adhesion Kinase Subfamily

, 1995
Hiroko Sasaki, Kazuko Nagura, Masaho Ishino, Hirotoshi Tobioka, Kiyoshi Kotani, Terukatsu Sasaki   +5 more
openalex   +1 more source

State-specific Monoclonal Antibodies Identify an Intermediate State in Epsilon Protein Kinase C Activation [PDF]

, 2004
Miriam C. Souroujon, Lina Yao, Haibin Chen, Gerda Endemann, Hanita Khaner, Virginie Geeraert, Deborah Schechtman, Adrienne S. Gordon, Ivan Diamond, Daria Mochly‐Rosen   +9 more
openalex   +1 more source

Genome-wide identification of the mitogen-activated protein kinase kinases in pear and their functional analysis in response to black spot

, 2023
Zan Zhang, Qiming Chen, LuTing Jia, Ming Qian, Qinghai Qiao, Xiaosan Huang, Shaoling Zhang   +6 more
openalex   +1 more source

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source

Discriminating activating, deactivating and resistance variants in protein kinases. [PDF]

Genome Med
Singh G, Schmenger T, Gonzalez-Sanchez JC, Kutkina A, Bremec N, Diwan GD, Mozas P, López C, Siebert R, Sotillo R, Russell RB.   +10 more
europepmc   +2 more sources

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Threonine 180 Is Required for G-protein-coupled Receptor Kinase 3- and β-Arrestin 2-mediated Desensitization of the μ-Opioid Receptor in Xenopus Oocytes

, 2001
Jeremy Celver, Janet Lowe, Abraham Kovoor, Vsevolod V. Gurevich, Charles Chavkin   +4 more
openalex   +1 more source