Results 191 to 200 of about 6,714,405 (407)

Editorial: Mitogen Activated Protein Kinases

Frontiers in Cell and Developmental Biology, 2017
Ana Cuenda, José M. Lizcano, José Lozano   +2 more
doaj   +1 more source

The substrate specificity of adenosine 3′:5′-cyclic monophosphate-dependent protein kinase of rabbit skeletal muscle [PDF]

, 1977
Stephen J. Yeaman, Philip Cohen, David C. Watson, Gordon H. Dixon   +3 more
openalex   +1 more source

Comprehensive profiling of lncRNAs and mRNAs enriched in small extracellular vesicles for early noninvasive detection of colorectal cancer: diagnostic panel assembly and extensive validation

Molecular Oncology, EarlyView.
Small extracellular vesicles are a promising source of diagnostic molecules. We conducted a comprehensive study, including transcriptome profiling and RT‐qPCR validation on large cohorts of samples. Diagnostic panels enabling sensitive detection of colorectal cancer and precancerous lesions were established. Some molecules were differentially expressed
Petra Vychytilova‐Faltejskova, Marketa Pavlikova, Lucie Pifkova, Robin Jugas, Tana Machackova, Lenka Radova, Milana Sachlova, Renata Bartosova, Tetiana Samoilenko, Zuzana Feckova, Jana Orlickova, Erika Slamova, Elleni Ponechal Michu, Dagmar Al Tukmachi, Michaela Ruckova, Martina Vodinska, Jan Kotoucek, Tina Catela Ivkovic, Marie Boudna, Lucia Bohovicova, Teodor Stanek, Jana Halamkova, Martin Svoboda, Vladimir Prochazka, Tomas Grolich, Zdenek Kala, Ondrej Slaby   +26 more
wiley   +1 more source

Effect of adenosine 3′,5′-cyclic monophosphate derivatives on α-amylase release, protein kinase and cyclic nucleotide phosphodiesterase activity from rat parotid tissue

, 1976
Fred R. Butcher, Molly Thayer, John M. Goldman   +2 more
openalex   +1 more source

Protein kinases and phosphatases: The Yin and Yang of protein phosphorylation and signaling

Cell, 1995
T. Hunter
semanticscholar   +1 more source

The specificities of small molecule inhibitors of the TGF beta and BMP pathways [PDF]

, 2011
Sapkota, Gopal P., Traynor, Ryan, Vogt, Janis   +2 more
core   +2 more sources

Brassinosteroid signalling [PDF]

, 2020
Kim, Eun-Ji, Russinova, Eugenia
core   +2 more sources

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

Protein kinases: mechanisms and downstream targets in inflammation-mediated obesity and insulin resistance

Molecular and Cellular Biochemistry, 2016
K. Nandipati, S. Subramanian, D. Agrawal
semanticscholar   +1 more source

The critical role of DNA damage‐inducible transcript 4 (DDIT4) in stemness character of leukemia cells and leukemia initiation

Molecular Oncology, EarlyView.
Stemness properties, including quiescence, self‐renewal, and chemoresistance, are closely associated with leukemia relapse. Here, we demonstrate that DNA damage‐inducible transcript 4 (DDIT4) is induced in the hypoxic bone marrow niche and is essential for maintaining the stemness of AML1‐ETO9a leukemia cells.
Yishuang Li, Zhijie Cao, Haiyan Xing, Zhenya Xue, Wenbing Liu, Jiayuan Chen, Yihan Mei, Runxia Gu, Hui Wei, Shaowei Qiu, Min Wang, Qing Rao, Jianxiang Wang   +12 more
wiley   +1 more source