Results 151 to 160 of about 2,399,730 (304)

Protein Tyrosine Phosphatase 2 (SHP-2) Moderates Signaling by gp130 but Is Not Required for the Induction of Acute-Phase Plasma Protein Genes in Hepatic Cells

Molecular and Cellular Biology, 1998
Hongkyun Kim, T. Hawley, R. Hawley, H. Baumann   +3 more
semanticscholar   +1 more source

Stromal‐Derived IL‐8 Promotes M2 Macrophage Polarization via the RhoA/MRTF‐A/SRF Transcriptional Axis to Impair CD8+ T Cell Cytotoxicity in Lung Cancer

Advanced Science, EarlyView.
In the recondite pulmonary neoplastic milieu, DESMIN+ cancer‐associated fibroblasts function as the paramount stromal source of IL‐8, precipitating a deleterious immunological metamorphosis by engaging CXCR2 receptors on the myeloid lineage. This paracrine stimulus triggers a mechanotransduction cascade characterized by RhoA‐dependent actin ...
Xuyu Gu, Qiyu Fang, Jia Yu, Ting Yu, Huashan Shi, Kaiqi Jin, Lei Jiang, Wentian Zhang   +7 more
wiley   +1 more source

Modulation of protein phosphatase 1 gamma 2 during cell division of cervical cancer HeLa cells

Contemporary Oncology, 2021
Saurabh Kumar Agnihotri, Parmita Kar, Manish Singh, Garima Pant, Kalyan Mitra, Madan Lal Brahma Bhatt, Monika Sachdev   +6 more
doaj   +1 more source

Perivascular Matrix Densification Dysregulates Angiogenesis and Activates Pro‐Inflammatory Endothelial Cells

Advanced Science, EarlyView.
Perivascular matrix densification promotes the emergence of aberrant endothelial tip cells (ATECs) that invade and persist within fibrotic microenvironments. Using in vivo lineage tracing and a human microvessel model, this study shows that fibrous matrix cues destabilize VE‐cadherin–mediated junctions to gate TGF‐β signaling, inducing a pro ...
Jingyi Xia, William Y. Wang, Kyle A. Jacobs, Kairav Maniar, Daphne Lin, Evan H. Jarman, Daniel L. Matera, Kristen Loesel, Christopher D. Davidson, Harrison L. Hiraki, Xiaotian Tan, Eve H. Shikanov, Robert N. Kent, Carole Parent, Xudong Fan, Ariella Shikanov, Matthew L. Kutys, Brendon M. Baker   +17 more
wiley   +1 more source

Inhibition of Trypanosoma evansi Protein-Tyrosine Phosphatase by Myristic Acid Analogues Isolated from Khaya senegalensis and Tamarindus indica

Journal of Experimental Pharmacology, 2019
Emeka John Dingwoke,1 Fatima Amin Adamude,2 Chimee Ethel Chukwuocha,1 Ahmed Adamu Ambi,1 Nwobodo Ndubuisi Nwobodo,3,4 Abdullahi Balarabe Sallau,1 Humphrey Chukwuemeka Nzelibe1 1Department of Biochemistry, Faculty of Life Sciences, Ahmadu Bello University,
Dingwoke EJ, Adamude FA, Chukwuocha CE, Ambi AA, Nwobodo NN, Sallau AB, Nzelibe HC   +6 more
doaj  

Mitogen-Activated Protein Kinase Phosphatase 2 Regulates the Inflammatory Response in Sepsis

Infection and Immunity, 2010
Timothy T. Cornell, Paul E Rodenhouse, Q. Cai, Lei Sun, T. Shanley   +4 more
semanticscholar   +1 more source

Adipocyte‐Derived Leptolin Enhances Energy Expenditure and Prevents Obesity

Advanced Science, EarlyView.
We identified a novel adipokine, which we named leptolin. In humans, leptolin levels in white adipose tissue were positively correlated with exercise and negatively associated with body mass index. We observed elevated leptolin in serum from athletes and lower leptolin in serum from obese individuals.
Jiarui Liu, Bingwei Wang, Zhijie Su, Xiaoxv Han, Miao He, Yun Zhao, Yujia Hou, Daotong Li, Weiguang Zhang, Lihua Qin, Ke Wang, Yanchun Li, Yi Yan, Siwang Yu, Xiaoshuai Huang, Tairan Yuwen, Jianyuan Luo, Ruimao Zheng   +17 more
wiley   +1 more source

Protein Tyrosine Phosphatase-2 [PDF]

, 2018
openaire   +1 more source

Protein phosphatase 2 (PPP2CA; PPP2; PP2A) [PDF]

Science-Business eXchange, 2009
openaire   +1 more source

Dopamine regulates phosphorylation of VEGF receptor 2 by engaging Src-homology-2-domain-containing protein tyrosine phosphatase 2

Journal of Cell Science, 2009
Sutapa Sinha, P. Vohra, Resham Bhattacharya, S. Dutta, S. Sinha, D. Mukhopadhyay   +5 more
semanticscholar   +1 more source