Results 191 to 200 of about 3,958,355 (265)

Psychotic Disorder Secondary to Cerebral Venous Thrombosis Caused by Primary Thrombophilia in a Pediatric Patient with Protein S Deficiency and an MTHFR p.Ala222Val Variant: A Case Report. [PDF]

Hematol Rep
Martínez-Pascual D, Solis-Mendoza AD, Calderon-García J, Sommer B, Calixto E, Martinez-Enriquez ME, Aquino-Gálvez A, Solis-Chagoyan H, Montaño LM, Romero-Martinez BS, Jaimez R, Flores-Soto E.   +11 more
europepmc   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Proteome and Metabolome Profiling of Anticoagulant Disorders Induced by Familial Protein S Deficiency. [PDF]

J Proteome Res
Zhang C, Zhang Y, Liu B, Chen Y, Xie Y, Huang H, Liu Z, He Z.   +7 more
europepmc   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Unfolded von Willebrand factor binds protein S and reduces anticoagulant activity. [PDF]

Blood Vessel Thromb Hemost
Sim MMS, Mollica MY, Alfar HR, Hollifield M, Chung DW, Fu X, Gandhapudi S, Coenen DM, Prakhya KS, Mahmood DFD, Banerjee M, Peng C, Li X, Thornton AC, Porterfield JZ, Sturgill JL, Sievert GA, Barton-Baxter M, Zheng Z, Campbell KS, Woodward JG, López JA, Whiteheart SW, Garvy BA, Wood JP.   +24 more
europepmc   +1 more source

A Case of Acute Renal Infarct Secondary to Protein S Deficiency. [PDF]

Indian J Nephrol
Mathews DS, George N, Jeyasekharan R.
europepmc   +1 more source

Investigation of a novel PROS1 splicing variant in a patient with protein S deficiency. [PDF]

Hum Genome Var
Niida Y, Fujita W, Togi S, Ura H.
europepmc   +1 more source

Coexistence Between Antiphospholipid Syndrome and Protein S Deficiency in a Patient With Transverse Sinus Thrombosis: A Rare Association. [PDF]

Clin Case Rep
Mahmoud ZIT, Abdalla YA, Omer HBGE, Ali OMA, Suliman MSA, Awad A, Hamza SB, Elmobark SOE, Gafar M, Osman AO.   +9 more
europepmc   +1 more source

Autoantibodies to protein S may explain rare cases of coagulopathy following COVID-19 vaccination. [PDF]

Sci Rep
Yalcinkaya A, Cavalli M, Aranda-Guillén M, Cederholm A, Güner A, Rietrae I, Mildner H, Behere A, Eriksson O, Gonzalez L, Mugabo CH, Johnsson A, Lakshmikanth T, Brodin P, Wadelius M, Hallberg P, Landegren N.   +16 more
europepmc   +1 more source