Molecular interactions between the constituents of small ribosomal subunit [PDF]
Availability of high-resolution crystal structures of ribosomal subunits of different species opens a route to investigate about molecular interactions between its constituents and stabilization strategy. Structural analysis of the small ribosomal subunit shows that primary binder proteins are mainly employed in stabilizing the folded ribosomal RNA by ...
arxiv
Perturbation of the secondary structure of the scrapie prion protein under conditions that alter infectivity. [PDF]
Marı́a Gasset+3 more
openalex +1 more source
The Mathematics of Secondary Structures in Proteins [PDF]
Magdalena Toda, Bhagya Athukorallage
openaire +2 more sources
TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach+8 more
wiley +1 more source
A Comprehensive System for Secondary Structure Analysis of Protein Models [PDF]
In protein structure analysis, the accurate characterization of secondary structure elements is crucial for understanding protein function and dynamics. This paper presents a software system designed for the comprehensive analysis of the secondary structure of protein models.
arxiv
Isoprenyl diphosphate synthases: Protein sequence comparisons, a phylogenetic tree, and predictions of secondary structure [PDF]
Anjun Chen+2 more
openalex +1 more source
EMT‐associated bias in the Parsortix® system observed with pancreatic cancer cell lines
The Parsortix® system was tested for CTC enrichment using pancreatic cancer cell lines with different EMT phenotypes. Spike‐in experiments showed lower recovery of mesenchymal‐like cells. This was confirmed with an EMT‐inducible breast cancer cell line.
Nele Vandenbussche+8 more
wiley +1 more source
MCP: a Multi-Component learning machine to Predict protein secondary structure [PDF]
The Gene or DNA sequence in every cell does not control genetic properties on its own; Rather, this is done through translation of DNA into protein and subsequent formation of a certain 3D structure. The biological function of a protein is tightly connected to its specific 3D structure.
arxiv
Molecular cloning of cDNA and analysis of protein secondary structure of Candida albicans enolase, an abundant, immunodominant glycolytic enzyme [PDF]
Paula Sundstrom, George R. Aliaga
openalex +1 more source
Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon+13 more
wiley +1 more source