Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey +12 more
wiley +1 more source
PALSSE: A program to delineate linear secondary structural elements from protein structures [PDF]
Indraneel Majumdar +2 more
openalex +1 more source
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu +8 more
wiley +1 more source
2DProts: database of family-wide protein secondary structure diagrams. [PDF]
Hutařová Vařeková I +6 more
europepmc +1 more source
A new protein folding algorithm based on hydrophobic compactness: Rigid Unconnected Secondary Structure Iterative Assembly (RUSSIA). II: Applications [PDF]
Denis Znamenskiy +3 more
openalex +1 more source
Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome
ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon +12 more
wiley +1 more source
Deep Ensemble Learning with Atrous Spatial Pyramid Networks for Protein Secondary Structure Prediction. [PDF]
Guo Y, Wu J, Ma H, Wang S, Huang J.
europepmc +1 more source
Species-specific protein secondary structure prediction
Mariana Barssoum
openalex +2 more sources
SNUPN‐Related Muscular Dystrophy: Novel Phenotypic, Pathological and Functional Protein Insights
ABSTRACT Objective SNUPN‐related muscular dystrophy or LGMDR29 is a new entity that covers from a congenital or childhood onset pure muscular dystrophy to more complex phenotypes combining neurodevelopmental features, cataracts, or spinocerebellar ataxia. So far, 12 different variants have been described.
Nuria Muelas +18 more
wiley +1 more source
Evaluation of key aroma compounds and protein secondary structure in the roasted Tan mutton during the traditional charcoal process. [PDF]
Wang YR, Wang SL, Luo RM.
europepmc +1 more source

