Results 161 to 170 of about 4,543,051 (305)

Fusogenic RNA Nanomodules for Fusion‐Mediated and Multiplexed siRNA Delivery

Advanced Functional Materials, EarlyView.
A fusogenic lipid‐layered RNA nanomodules (L‐CRAMs) enable high‐capacity and long‐lasting siRNA delivery through membrane fusion. These nanomodules carry exceptionally large siRNA payloads, avoid conventional endosomal uptake, and release multiple functional siRNAs through Dicer‐mediated processing.
Sunghyun Moon, Iksoo Jang, Taehyeon Kim, Nayoung Yoon, Kyuha Yum, Jong Bum Lee   +5 more
wiley   +1 more source

ERAD-level gene switches for on-demand protein secretion and rapidly controlled gene therapies. [PDF]

Nat Commun
Gao T, Li S, Fan Y, Yan W, He M, Zhang Q, Li Y, Liu Q, Wang P, Jiang J, Zhang L, Zhou Y, Zhao L, Xiong Q, Wu Y, Yuan S, Fang S, Tang H, Fussenegger M, Wang H, Shao J, Xie M.   +21 more
europepmc   +1 more source

Dual‐Layer Conducting and Redox Polymer Bioanodes for Synergistic Enhancement of Microbial Extracellular Electron Transfer

Advanced Functional Materials, EarlyView.
A hybrid PEDOT/Fc‐LPEI conducting/redox polymer bioanode synergistically improves microbial extracellular electron transfer (EET) in Shewanella oneidensis MR‐1. The dual‐layer interface delivers 18‐fold higher current output and 27‐fold greater charge collected than bare carbon felt, highlighting an effective strategy for high‐performance ...
Shenghan Gu, Saman Azhari, Kuniaki Nagamine, Takeo Miyake, Gábor Méhes   +4 more
wiley   +1 more source

Unconventional Protein Secretion in the Central Nervous System: Mechanisms and Roles in Physiology and Disease. [PDF]

J Neurochem
Krauklis SA, Keçeli SK, Campbell EM, Abbineni PS.   +3 more
europepmc   +1 more source

Protein Secretion by the Pancreas [PDF]

Science, 1980
openaire   +2 more sources

Multifunctional Neutrophil Nanovesicles Induce Remodeling of Tumor Immune Microenvironment and Synergistic Multimodal Tumor Therapy

Advanced Functional Materials, EarlyView.
Schematic illustration of the engineered RN@FDT for multimodal tumor therapy. a) Fabrication of FD&DOX/TFA‐loaded RGD‐NNV (RN@FDT) and the light‐triggered disassemble of RN@FDT. b) After internalized by tumor cells, RN@FDT are disintegrated under NIR‐II laser irradiation to boost PTT and induce cell apoptosis.
Jiahui Zhang, Cheng Ji, Xin‐Jian Fang, Yu Qian, Jiayuan Shi, Wenhui Liu, Baiyuan Fan, Yuan Zhong, Jiayi Wang, Dan Yu, Maoye Wang, Min Fu, Xiaoxin Zhang, Runbi Ji, Hélder A. Santos, Hongbo Zhang, Xu Zhang   +16 more
wiley   +1 more source

Endoplasmic reticulum and Golgi stress signaling-mediated regulation of protein secretion. [PDF]

Cell Mol Biol Lett
Bakambamba K, Nivet M, Martin S, Lafont E, Chevet E, Avril T.   +5 more
europepmc   +1 more source

Biomimetic Core–Shell Liposome Nanoparticles Deplete Lipoproteins and Enhance the Purity of Extracellular Vesicles from Human Blood

Advanced Functional Materials, EarlyView.
Lipoprotein‐mimicking nanoparticles (SL‐NPs), comprising Fe3O4@SiO2 cores coated with liposomal bilayers, selectively capture lipoproteins through protein corona formation. The resulting SL‐NP‐lipoprotein complexes can be removed by low‐speed centrifugation, thereby enhancing the purity of small extracellular vesicles (sEVs) isolated from human serum ...
Man‐Di Wang, Andrew J. Perciaccante, David Inman, Bong Hwan Sung, Alissa M. Weaver, Suzanne M. Ponik, Ying Ge, Song Jin   +7 more
wiley   +1 more source

Distinctive amino acid residue periodicities in terminal sequences of type III and type I secreted proteins from proteobacteria

Open Life Sciences, 2007
Andersone Inara, Zikmanis Peteris
doaj   +1 more source

Endurance exercise elicits a hepatic memory associated with improved metabolic function and protein secretion. [PDF]

Mol Metab
Huang YH, Weidenhamer CJ, Dabirian N, Kasperek M, Molina D, Deyhle S, Natua S, Amengual J, Allen JM, Kalsotra A, Hernández-Saavedra D.   +10 more
europepmc   +1 more source